| Texto completo | |
| Autor(es): |
Gnocchi, Karla Giavarini
;
Boldrini-Franca, Johara
;
Passos, Larissa Souza
;
Gomes, Aline Silva
;
Coppo, Gabriel Carvalho
;
Pereira, Tatiana Miura
;
Chippari-Gomes, Adriana Regina
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 100, p. 7-pg., 2023-04-19. |
| Resumo | |
The present study aimed to evaluate the toxicity of Mn (6.65 mg/L) at different exposure times (96 h, 7, 14, and 21 days) and evaluate its possible toxic effects on the fish Astyanax lacustris through multi-biomarkers and the maximum critical temperature (CT Max). The results show an increase in the Mn accumulation (liver and gills) with increasing exposure time. The glutathione S-transferase (GST) activity showed differences in the group exposed to Mn for 96 h compared to the group exposed for 21 days. The acetylcholinesterase (AChE) activity increased in the fish exposed for 7 days compared to the control group. On the other hand, no genotoxic changes were observed. The CT Max showed that the loss of equilibrium of 50% of the fish occurs at a temperature of 39oC, with and without the Mn presence. Furthermore, the catalase gene expression (oxidative stress) did not show alterations. (AU) | |
| Processo FAPESP: | 21/14239-1 - Efeitos da interação entre organofosforados sintéticos e natural em Oreochromis niloticus (Teleostei: Cichlidae) |
| Beneficiário: | Larissa Souza Passos |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |