Ovaries of guppies (Poecilia reticulata) investigated in pre-embryonic, embryonic and post-embryonic stages after exposure to maghemite nanoparticles (y-Fe2O3) associated with Roundup (R) and glyphosate, followed by recovery period evaluation

Autor(es)

da Silva, Victoria Costa ; de Lima-Faria, Joao Marcos ; Guimaraes, Lucas Nunes ; Costa, Matheus Santos ; de Lima, Phamella Neres ; Simoes, Karina ; Oliveira de Jesus, Lazaro Wender ; Teixeira de Saboia-Morais, Simone Maria

• Tipo de documento: Artigo Científico
• Fonte: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 100, p. 12-pg., 2023-05-17.

Resumo

Iron oxide nanoparticles (IONP) are promising alternatives to environmental remediation, so this study in-vestigates IONP single and associated to contaminants, in this case, glyphosate (GLY) and Roundup (R) (GBH) in Poecilia reticulata (guppy). The guppies have internal development, therefore this study analyzed female gonads to establish the developmental stages of P. reticulata and evaluate effects of exposure (7, 14 and 21 days) and post-exposure (same period) to the treatments with Iron ions 0.3 mg Fe/L (IFe); IONP 0.3 mg Fe/L; IONP 0.3 mgFe/L + GBH 0,65 mgGLY/L (IONP+GBH1); IONP 0.3 mgFe/L + GBH 1.30 mgGLY/L (IONP+GBH2); and IONP 0.3 mgFe/L + GLY 0.65 mg/L (IONP+GLY). The development was organized in immature, development, and gestation phases. The damage in all treatments after 21 days of exposure was evident in reaction patterns regressive inflammatory, and circulatory including total histopathologic index of liver, nevertheless there was a damage recovery trend during post-exposure period. (AU)

• Processo FAPESP: 19/24180-4 - Múltiplos biomarcadores celulares e teciduais em guppy (Poecilia reticulata) expostos por longo período a nanopartículas metálicas associadas a glifosato, microscistina-LR e cilindrospermopsina (NANOMBI)
• Beneficiário: Marisa Narciso Fernandes
• Modalidade de apoio: Auxílio à Pesquisa - Regular