| Texto completo | |
| Autor(es): |
Pessoa, Jassiara da Silva
;
de Oliveira, Caroline Frere Martiniuc
;
Mena-Chalco, Jesus Pascual
;
de Carvalho, Joao Carlos Monteiro
;
Ferreira-Camargo, Livia Seno
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Biotechnology and Applied Biochemistry; v. N/A, p. 13-pg., 2023-06-19. |
| Resumo | |
The green microalga Chlamydomonas reinhardtii is a model microorganism for several areas of study. Among the different microalgae species, it presents advantageous characteristics, such as genomes completely sequenced and well-established techniques for genetic transformation. Despite that, C. reinhardtii production is still not easily commercially viable, especially due to the low biomass yield. So far there are no reports of scientometric study focusing only on C. reinhardtii biomass production process. Considering the need for culture optimization, a scientometric research was conducted to analyze the papers that investigated the growth regimes effects in C. reinhardtii cultivation. The search resulted in 130 papers indexed on Web of Science and Scopus platforms from 1969 to December 2022. The quantitative analysis indicated that the photoautotrophic regime was the most employed in the papers. However, when comparing the three growth regimes, the mixotrophic one led to the highest production of biomass, lipids, and heterologous protein. The production of bioproducts was considered the main objective of most of the papers and, among them, biomass was the most frequently investigated. The highest biomass production reported among the papers was 40 g L-1 in the heterotrophic growth of a transgenic strain. Other culture conditions were also crucial for C. reinhardtii growth, for instance, temperature and cultivation process. (AU) | |
| Processo FAPESP: | 19/19308-1 - Avaliação de Chlamydomonas reinhardtii como plataforma de produção da proteína recombinante filgrastima |
| Beneficiário: | Caroline Frere Martiniuc de Oliveira |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 16/12992-6 - Chlamydomonas reinhardtii como plataforma de produção de biofármacos de interesse nacional |
| Beneficiário: | Lívia Seno Ferreira Camargo |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 19/13822-5 - Acúmulo da proteína recombinante terapêutica somatotropina em Chlamydomonas reinhardtii |
| Beneficiário: | Jassiara da Silva Pessoa |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |