Holmium-doped 58S glass-derived foam-like scaffolds

Autor(es)

Baino, Francesco ; Marchi, Juliana ; Borges, Roger ; Verne, Enrica

• Tipo de documento: Artigo Científico
• Fonte: Materials Letters; v. 341, p. 3-pg., 2023-03-22.

Resumo

Biocompatible implantable glasses doped with rare earth elements (e.g. holmium) are regarded as promising biomaterials for advanced medical therapies. In this work, Ho-containing scaffolds based on the 58S sol-gel glass composition were fabricated for the first time through sponge replication followed by sinter-crystallization, which was associated to the formation of CaSiO3. The obtained materials exhibited high porosity (86 vol%), trabecular pore-strut 3D architecture and compressive strength (around 1 MPa) comparable to that of osseous tissue, making them promising candidates for use in bone applications. (AU)

• Processo FAPESP: 20/00329-6 - Desenvolvimento de compósito multifuncional injetável para tratamento de câncer ósseo por hipertermia e braquiterapia associado à reparação óssea
• Beneficiário: Juliana Marchi
• Modalidade de apoio: Auxílio à Pesquisa - Regular