| Texto completo | |
| Autor(es): |
Matos, Adaias Oliveira
;
Rangel, Elidiane Cipriano
;
Ricardo Barao, Valentim Adelino
;
Gregory, Richard Lee
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | DENTAL MATERIALS JOURNAL; v. 42, n. 2, p. 8-pg., 2023-04-01. |
| Resumo | |
Because nicotine upregulates the growth of most oral bacteria, this in vitro study investigated the antimicrobial effect of chlorhexidine-doped thin film on commercially pure titanium against Fusobacterium nucleatum (F. nucleatum) biofilm supplemented with different concentrations of nicotine (0, 1, and 2 mg/mL). Biofilms were formed on a chlorhexidine-doped thin film on commercially-pure-titanium discs and compared to the control groups. Biofilm viability, total biofilm growth using a spectrophotometer, extracellular polysaccharide content, and pH variations were assessed as dependent variables. Data were submitted to ANOVA and Tukey honest significant difference tests (a=0.05). F. nucleatum biofilm growth was inhibited when exposed to chlorhexidine-doped thin film (p<0.05). Biofilm supplemented with nicotine did not impact the synthesis of EPS on the same type of treatment (p>0.05). The pH values were significantly increased with the increase of nicotine concentration (p<0.05). Chlorhexidine-doped thin film was effective in reducing F. nucleatum biofilm supplemented with nicotine. (AU) | |
| Processo FAPESP: | 17/21894-0 - Potencial antimicrobiano e de biocompatibilidade de filmes de hexametildisiloxano incorporados a clorhexidina em superfície de titânio usando um modelo de epitélio oral gengival co-infectado reconstituído in vitro |
| Beneficiário: | Adaias Oliveira Matos |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |
| Processo FAPESP: | 16/06117-5 - Desenvolvimento de filmes de hexametildisiloxano incorporados com clorexidina na superfície de titânio: potencial antimicrobiano e citotoxicidade |
| Beneficiário: | Adaias Oliveira Matos |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |