Luminomagnetic Silica-Coated Heterodimers of Core/Shell FePt/Fe3O4 and CdSe Quantum Dots as Potential Biomedical Sensor

Autor(es)

Secco de Souza, Caio Guilherme ; Souza, Joao Batista, Jr. ; Beck, Watson, Jr. ; Varanda, Laudemir Carlos

• Tipo de documento: Artigo Científico
• Fonte: Journal of Nanomaterials; v. 2017, p. 9-pg., 2017-01-01.

Resumo

We report the synthesis of a new multifunctional nanomaterial based on silica-coated FePt/Fe3O4 - CdSe heteronanostructures, combining luminescent and magnetic properties in a promising bifunctional sensor for biomedical applications. Spherical Fe3O4-coated FePt (FePt/Fe3O4) superparamagnetic nanoparticles (10.8 +/- 1.5 nm) with high saturation magnetization and controlled size and shape were obtained using thermal decomposition coupled with seed-mediated growth method. Luminescent property was added to the nanomaterial by using the FePt/Fe3O4 magnetic core as seed and growing the CdSe quantum dots (2.7 +/- 0.6 nm) onto its surface in a heterodimer-like structure using the hot-injection approach. The FePt/Fe3O4 - CdSe luminomagnetic heteronanostructures were coated with silica shell using the reverse-micelle microemulsion route to avoid solvent-quenching effects. After silica coating, the water-dispersible heteronanostructures showed a diameter of 25.3 +/- 2 nm, high colloidal stability, magnetic saturation of around 11 emu g(-1), and photoluminescence in the blue-green region, as expected for potential bifunctional platform in biomedical applications. The saturation magnetization of heteronanostructures can be increased to 28 emu g(-1) by annealing at 550 degrees C due to the presence of the FePt phase. (AU)

• Processo FAPESP: 13/01284-2 - Nanopartículas teranósticas a base de óxido de ferro superparamagnético para terapia de câncer da pele via hipertermia magnética
• Beneficiário: Laudemir Carlos Varanda
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 12/02093-3 - Síntese de nanoestruturas core@shell de Co@Au (superparamagnéticas) e CdSe@ZnS (quantum dots) visando aplicações antineoplásicas
• Beneficiário: João Batista Souza Junior
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 07/07919-9 - Nanocristais magnéticos coloidais: obtenção de nanoesferas, nanofios e nanobastões auto-organizados e funcionalizados com macromoléculas para aplicação em gravação magnética avançada, biotecnologia e biomedicina
• Beneficiário: Laudemir Carlos Varanda
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores