| Texto completo | |
| Autor(es): |
de Carvalho, Marcelo P. N.
;
Moura, Quezia
;
Fernandes, Miriam R.
;
Sellera, Fabio P.
;
Pagotto, Ana Helena
;
Stuginski, Daniel R.
;
Castro, Rafael A.
;
Sant'Anna, Savio S.
;
Grego, Kathleen F.
;
Lincopan, Nilton
Número total de Autores: 10
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE; v. 15, p. 2-pg., 2018-12-01. |
| Resumo | |
Objectives: The widespread dissemination of extended-spectrum beta-lactamase-producing Enterobacteriaceae has become a major issue in veterinary medicine. However, until now, there has been no report of bacteria with such a phenotype in infected snakes. The aim of this study was to report the first draft genome sequence of an Enterobacter cloacae isolate (SERP1) recovered from a snake with infectious stomatitis. Methods: The whole genome of E. cloacae strain SERP1 was sequenced on an Illumina NextSeq platform and was de novo assembled using CLC NGS Cell v.10. Data analysis was performed using online tools from the Center of Genomic Epidemiology. Results: The genome size was calculated at 4966 856 bp, containing a total of 4796 protein-coding sequences. The strain was assigned to sequence type 279 (ST279) and, besides the clinically relevant bla(CTX-M-15) and aac(6')-Ib-cr genes, it also presented resistance genes to beta-lactams, aminoglycosides, phenicols, sulphonamides, tetracyclines, trimethoprim, quinolones and fosfomycin. Conclusion: These data offer novel information regarding multidrug-resistant E. cloacae dissemination in wild animals and might contribute to further comparative genomic analysis. (C) 2018 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 16/08593-9 - Pan-resistoma de Klebsiella pneumoniae e Escherichia coli produtoras de beta-lactamases (KPC-2, CTX-M-8, CTX-M-15) endêmicas no Brasil |
| Beneficiário: | Nilton Erbet Lincopan Huenuman |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 15/13527-2 - Relação ancestral, pan-resistoma plasmidial de Escherichia coli produtora de b-lactamases de espectro estendido (CTX-M) e métodos de cura plasmidial |
| Beneficiário: | Miriam Rodriguez Fernandes |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |