Visible light-promoted reactions with diazo compounds: a mild and practical strategy towards free carbene intermediates

Autor(es)

Yang, Zhen ; Stivanin, Mateus L. ; Jurberg, Igor D. ; Koenigs, Rene M.

• Tipo de documento: Artigo Científico
• Fonte: CHEMICAL SOCIETY REVIEWS; v. 49, n. 19, p. 15-pg., 2020-10-07.

Resumo

Carbenes are important intermediates in organic chemistry and have been widely applied in various types of organic reactions, ranging from cycloaddition reactions and sigmatropic rearrangements to C-H functionalizations, thus allowing the rapid construction of densely functionalized molecules. Over the past decades, remarkable progress has been achieved in metal-catalyzed carbene transfer reactions. Nevertheless, realizing these transformations under milder and/or greener conditions is still highly desirable. Only recently, visible light-promoted carbene transfer reactions of diazo compoundsviafree carbene intermediates have emerged as a practical, mild and powerful tool. In this tutorial review, we summarize the latest advances in the area, aiming at providing a clear overview on reaction design, mechanistic scenarios and potential future developments. (AU)

• Processo FAPESP: 19/01235-8 - Fotoquímica com luz visível empregando diazocompostos doadores-aceptores
• Beneficiário: Igor Dias Jurberg
• Modalidade de apoio: Auxílio à Pesquisa - Regular