| Texto completo | |
| Autor(es): |
Camargo, Lucas
;
Pacheco-Barrios, Kevin
;
Marques, Lucas M.
;
Caumo, Wolnei
;
Fregni, Felipe
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | BIOMEDICINES; v. 12, n. 7, p. 15-pg., 2024-07-01. |
| Resumo | |
This study aimed to investigate clinical and physiological predictors of brain oscillatory activity in patients with fibromyalgia (FM), assessing resting-state power, event-related desynchronization (ERD), and event-related synchronization (ERS) during tasks. We performed a cross-sectional analysis, including clinical and neurophysiological data from 78 subjects with FM. Multivariate regression models were built to explore predictors of electroencephalography bands. Our findings show a negative correlation between beta oscillations and pain intensity; fibromyalgia duration is positively associated with increased oscillatory power at low frequencies and in the beta band; ERS oscillations in the theta and alpha bands seem to be correlated with better symptoms of FM; fatigue has a signature in the alpha band-a positive relationship in resting-state and a negative relationship in ERS oscillations. Specific neural signatures lead to potential clusters of neural adaptation, in which beta oscillatory activity in the resting state represents a more adaptive activity when pain levels are low and stimulus-evoked oscillations at lower frequencies are likely brain compensatory mechanisms. These neurophysiological changes may help to understand the impact of long-term chronic pain in the central nervous system and the descending inhibitory system in fibromyalgia subjects. (AU) | |
| Processo FAPESP: | 21/05897-5 - O déficit da inibição como marcador de neuroplasticidade na reabilitação |
| Beneficiário: | Lucas Murrins Marques |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |