| Texto completo | |
| Autor(es): |
Nazari-Vanani, Razieh
;
Negahdary, Masoud
Número total de Autores: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Environmental Research; v. 243, p. 35-pg., 2023-12-14. |
| Resumo | |
In recent years, pathogenic microorganisms have caused significant mortality rates and antibiotic resistance and triggered exorbitant healthcare costs. These pathogens often have high transmission rates within human populations. Rapid diagnosis is crucial in controlling and reducing the spread of pathogenic infections. The diagnostic methods currently used against individuals infected with these pathogens include relying on outward symptoms, immunological-based and, some biomolecular ones, which mainly have limitations such as diagnostic errors, time-consuming processes, and high-cost platforms. Electrochemical aptasensors and genosensors have emerged as promising diagnostic tools for rapid, accurate, and cost-effective pathogen detection. These bio-electrochemical platforms have been optimized for diagnostic purposes by incorporating advanced materials (mainly nanomaterials), biomolecular technologies, and innovative designs. This review classifies electro-chemical aptasensors and genosensors developed between 2021 and 2023 based on their use of different nanomaterials, such as gold-based, carbon-based, and others that employed other innovative assemblies without the use of nanomaterials. Inspecting the diagnostic features of various sensing platforms against pathogenic analytes can identify research gaps and open new avenues for exploration. (AU) | |
| Processo FAPESP: | 19/27021-4 - Projeto e fabricação de biossensores eletroquímicos para diagnóstico precoce de infarto do miocárdio e de Carcinoma Hepatocelular usando primers de microRNAs (miRNAs) como elemento de bioreconhecimento e arranjos de matrizes de nanoestruturas de ouro |
| Beneficiário: | Masoud Negahdary |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |