Overview of the economic burden of musculoskeletal pain in children and adolescents: a systematic review with meta-analysis

Autor(es)

Espirito Santo, Caique de Melo ; Santos, Veronica S. ; Kamper, Steven J. ; Williams, Christopher M. ; Miyamoto, Gisela C. ; Yamato, Tie P.

• Tipo de documento: Artigo Científico
• Fonte: Pain; v. 165, n. 2, p. 28-pg., 2024-02-01.

Resumo

Supplemental Digital Content is Available in the Text. Studies suggest a high economic burden among children and adolescents with musculoskeletal pain. There is no summary in the literature on the overall economic burden of musculoskeletal pain in children and adolescents. The aim of this systematic review of cost-of-illness studies was to synthesize the economic burden of musculoskeletal pain in children and adolescents. We conducted electronic searches on MEDLINE, EMBASE, CINAHL, EconLit, NHSEED, and HTA databases. We included cost-of-illness studies that estimated healthcare, patient/family, lost productivity, and/or societal costs in children and adolescents with musculoskeletal pain. The risk of bias was assessed with the Consolidated Health Economic Evaluation Reporting Standards checklist. All values were adjusted to the same reference year (2021) and converted to American Dollar. We included 45 cost-of-illness studies (n = 665,623). Twenty-two studies estimated the annual healthcare costs that ranged from $143 to $41,379 per patient. Nine studies estimated the annual patient/family costs that ranged from $287 to $27,972 per patient. Seven studies estimated the annual lost productivity costs that ranged from $124 to $4671 per patient. Nine studies estimated the annual societal costs that ranged from $1095 to $69,351 per patient. Children and adolescents with juvenile idiopathic arthritis and musculoskeletal pain had higher annual incremental healthcare costs than those without these conditions (mean difference: $3800 higher, 95% confidence interval [CI]: 50-7550; mean difference: $740 higher, 95% CI: 470-1,010, respectively). In conclusion, the estimated annual economic burden of children and adolescents with musculoskeletal pain ranged from $124 to $69,351. (AU)

• Processo FAPESP: 19/12049-0 - Prevalência e fatores prognósticos da dor musculoesquelética incapacitante em crianças e adolescentes na cidade de São Paulo
• Beneficiário: Verônica Souza Santos
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 21/08776-4 - Prevalência, custos e tratamento da dor musculoesquelética em crianças e adolescentes
• Beneficiário: Caique de Melo do Espirito Santo
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 17/17484-1 - Prevalência e fatores prognósticos da dor musculoesquelética em crianças e adolescentes na cidade de São Paulo
• Beneficiário: Tiê Parma Yamato
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores