Gold Catalysts for Selective Hydrogenations: The Role of Heterolytic H₂ Dissociation

Autor(es)

Luiz Fiorio, Jhonatan ; Guerra, Raiza Rosa Garcia ; Martin-Matute, Belen ; Rossi, Liane Marcia

• Tipo de documento: Artigo Científico
• Fonte: CHEMCATCHEM; v. N/A, p. 9-pg., 2024-10-26.

Resumo

Hydrogenations are fundamental transformations in organic synthesis, and the industrial applications span from food, petrochemical, fine chemicals to pharmaceuticals synthesis where hydrogenations of multifunctional molecules should be carried out in a chemoselective way. In this concept article we aim at providing an overview on the activation of molecular hydrogen (H2) via heterolytic dissociation, which is responsible to unlock high activity of gold catalysts for chemoselective hydrogenations. The key benefit of heterolytically dissociated H species is their preference for hydrogenating polar unsaturated groups like C=O, C=N, and C=S, as these polar bonds are ideal acceptors for proton and hydride pairs. We will provide examples on how to obtain enhanced chemoselectivity on alkynes, alpha, beta-unsaturated aldehydes and nitro-compounds hydrogenations with gold catalysts. (AU)

• Processo FAPESP: 14/50279-4 - Brasil Research Centre for Gas Innovation
• Beneficiário: Julio Romano Meneghini
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia
• Processo FAPESP: 18/26253-6 - Catálise cooperativa: uma alternativa para o desenvolvimento de catalisadores a base de ouro e metais de transição abundantes
• Beneficiário: Liane Marcia Rossi
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 20/15230-5 - Centro de Pesquisa e Inovação de Gases de Efeito Estufa - RCG2I
• Beneficiário: Julio Romano Meneghini
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia
• Processo FAPESP: 21/00675-4 - Arquitetura de materiais para armazenamento de energia eletroquímica e catálise
• Beneficiário: Roberto Manuel Torresi
• Modalidade de apoio: Auxílio à Pesquisa - Temático