| Texto completo | |
| Autor(es): |
Campos, Isabele S.
;
Fermi, Andrea
;
Ventura, Barbara
;
Moraes, Carlos A. F.
;
Ribeiro, Gabriel H.
;
Venancio, Tiago
;
Ceroni, Paola
;
Carlos, Rose M.
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Inorganic Chemistry; v. 63, n. 10, p. 9-pg., 2024-02-29. |
| Resumo | |
Herein, we present a novel ruthenium(II)-perylene dyad (RuPDI-Py) that combines the photophysical properties of pyrrolidine-substituted perylene diimide (PDI-Py) and the ruthenium(II) polypyridine complex [Ru(phen)(3)](2+). A comprehensive study of excited-state dynamics was carried out using time-resolved and steady-state methods in a dimethyl sulfoxide solution. The RuPDI-Py dyad demonstrated excitation wavelength-dependent photophysical behavior. Upon photoexcitation above 600 nm, the dyad exclusively exhibits the near-infrared (NIR) fluorescence of the (PDI)-P-1-Py state at 785 nm (tau(fl) = 1.50 ns). In contrast, upon photoexcitation between 350 and 450 nm, the dyad also exhibits a photoinduced electron transfer from the {[Ru(phen)(3)](2+)} moiety to PDI-Py, generating the charge-separated intermediate state {Ru(III)-(PDI-Py)(center dot-)} (4 mu s). This state subsequently decays to the long-lived triplet excited state (PDI)-P-3-Py (36 mu s), which is able to sensitize singlet oxygen (O-1(2)). Overall, tuning O-1(2) photoactivation or NIR fluorescence makes RuPDI-Py a promising candidate for using absorbed light energy to perform the desired functions in theranostic applications. (AU) | |
| Processo FAPESP: | 18/03424-0 - Complexos de Ru(II)-perilenodiimida para ativação do oxigênio singleto: terapia fotodinâmica e imagem celular no tratamento de Câncer Melanoma |
| Beneficiário: | Isabele Aparecida Soares de Campos |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 21/10586-9 - Investigação das propriedades dos estados excitados de díades doadoras-receptoras de rutênio(II)-perileno diimida |
| Beneficiário: | Isabele Aparecida Soares de Campos |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |