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The case for eliminating excessive worry as a requirement for generalized anxiety disorder: a cross-national investigation

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Ruscio, Ayelet Meron ; Rassaby, Madeleine ; Stein, Murray B. ; Stein, Dan J. ; Aguilar-Gaxiola, Sergio ; Al-Hamzawi, Ali ; Alonso, Jordi ; Atwoli, Lukoye ; Borges, Guilherme ; Bromet, Evelyn J. ; Bruffaerts, Ronny ; Bunting, Brendan ; Cardoso, Graca ; Chardoul, Stephanie ; de Girolamo, Giovanni ; de Jonge, Peter ; Gureje, Oye ; Haro, Josep Maria ; Karam, Elie G. ; Karam, Aimee ; Kiejna, Andrzej ; Kovess-Masfety, Viviane ; Lee, Sue ; Navarro-Mateu, Fernando ; Nishi, Daisuke ; Piazza, Marina ; Posada-Villa, Jose ; Sampson, Nancy A. ; Scott, Kate M. ; Slade, Tim ; Stagnaro, Juan Carlos ; Torres, Yolanda ; Viana, Maria Carmen ; Vladescu, Cristian ; Zarkov, Zahari ; Kessler, Ronald C.
Número total de Autores: 36
Tipo de documento: Artigo Científico
Fonte: PSYCHOLOGICAL MEDICINE; v. N/A, p. 12-pg., 2024-10-04.
Resumo

Background Around the world, people living in objectively difficult circumstances who experience symptoms of generalized anxiety disorder (GAD) do not qualify for a diagnosis because their worry is not 'excessive' relative to the context. We carried out the first large-scale, cross-national study to explore the implications of removing this excessiveness requirement.Methods Data come from the World Health Organization World Mental Health Survey Initiative. A total of 133 614 adults from 12 surveys in Low- or Middle-Income Countries (LMICs) and 16 surveys in High-Income Countries (HICs) were assessed with the Composite International Diagnostic Interview. Non-excessive worriers meeting all other DSM-5 criteria for GAD were compared to respondents meeting all criteria for GAD, and to respondents without GAD, on clinically-relevant correlates.Results Removing the excessiveness requirement increases the global lifetime prevalence of GAD from 2.6% to 4.0%, with larger increases in LMICs than HICs. Non-excessive and excessive GAD cases worry about many of the same things, although non-excessive cases worry more about health/welfare of loved ones, and less about personal or non-specific concerns, than excessive cases. Non-excessive cases closely resemble excessive cases in socio-demographic characteristics, family history of GAD, and risk of temporally secondary comorbidity and suicidality. Although non-excessive cases are less severe on average, they report impairment comparable to excessive cases and often seek treatment for GAD symptoms.Conclusions Individuals with non-excessive worry who meet all other DSM-5 criteria for GAD are clinically significant cases. Eliminating the excessiveness requirement would lead to a more defensible GAD diagnosis. (AU)

Processo FAPESP: 03/00204-3 - Estudo epidemiológico dos transtornos psiquiátricos na região metropolitana de São Paulo: prevalências, fatores de risco e sobrecarga social e econômica
Beneficiário:Laura Helena Silveira Guerra de Andrade
Modalidade de apoio: Auxílio à Pesquisa - Temático