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Perdomo, Sandra ; Abedi-Ardekani, Behnoush ; de Carvalho, Ana Carolina ; Ferreiro-Iglesias, Aida ; Gaborieau, Valerie ; Cattiaux, Thomas ; Renard, Helene ; Chopard, Priscilia ; Carreira, Christine ; Spanu, Andreea ; Nikmanesh, Arash ; Penha, Ricardo Cortez Cardoso ; Antwi, Samuel O. ; Ashton-Prolla, Patricia ; Canova, Cristina ; Chitapanarux, Taned ; Cox, Riley ; Curado, Maria Paula ; de Oliveira, Jose Carlos ; Dzamalala, Charles ; Fabianova, Elenora ; Ferri, Lorenzo ; Fitzgerald, Rebecca ; Foretova, Lenka ; Gallinger, Steven ; Goldstein, Alisa M. ; Holcatova, Ivana ; Huertas, Antonio ; Janout, Vladimir ; Jarmalaite, Sonata ; Kaneva, Radka ; Kowalski, Luiz Paulo ; Kulis, Tomislav ; Lagiou, Pagona ; Lissowska, Jolanta ; Malekzadeh, Reza ; Mates, Dana ; McCorrmack, Valerie ; Menya, Diana ; Mhatre, Sharayu ; Mmbaga, Blandina Theophil ; de Moricz, Andre ; Nyirady, Peter ; Ognjanovic, Miodrag ; Papadopoulou, Kyriaki ; Polesel, Jerry ; Purdue, Mark P. ; Rascu, Stefan ; Batista, Lidia Maria Rebolho ; Reis, Rui Manuel ; Pinto, Luis Felipe Ribeiro ; Rodriguez-Urrego, Paula A. ; Sangkhathat, Surasak ; Sangrajrang, Suleeporn ; Shibata, Tatsuhiro ; Stakhovsky, Eduard ; Swiatkowska, Beata ; Vaccaro, Carlos ; de Podesta, Jose Roberto Vasconcelos ; Vasudev, Naveen S. ; Vilensky, Marta ; Yeung, Jonathan ; Zaridze, David ; Zendehdel, Kazem ; Scelo, Ghislaine ; Chanudet, Estelle ; Wang, Jingwei ; Fitzgerald, Stephen ; Latimer, Calli ; Moody, Sarah ; Humphreys, Laura ; Alexandrov, Ludmil B. ; Stratton, Michael R. ; Brennnan, Paul

• Tipo de documento: Artigo Científico
• Fonte: CELL GENOMICS; v. 4, n. 3, p. 11-pg., 2024-03-13.

Resumo

Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Wholegenome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally. (AU)

• Processo FAPESP: 18/26297-3 - Estudos translacionais de câncer de cabeça e pescoço em América do Sul e Europa
• Beneficiário: Maria Paula Curado
• Modalidade de apoio: Auxílio à Pesquisa - Temático