| Texto completo | |
| Autor(es): Mostrar menos - |
Sacristan, C.
;
Ewbank, A. C.
;
Duarte-Benvenuto, A.
;
Sacristan, I.
;
Zamana-Ramblas, R.
;
Costa-Silva, S.
;
Ribeiro, V. Lanes
;
Bertozzi, C. P.
;
do Valle, R. del Rio
;
Castilho, P. V.
;
Colosio, A. C.
;
Marcondes, M. C. C.
;
Lailson-Brito, J.
;
Azevedo, A. de Freitas
;
Carvalho, V. L.
;
Pessi, C. F.
;
Cremer, M.
;
Esperon, F.
;
Catao-Dias, J. L.
Número total de Autores: 19
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| Tipo de documento: | Artigo Científico |
| Fonte: | SCIENTIFIC REPORTS; v. 14, n. 1, p. 13-pg., 2024-02-01. |
| Resumo | |
Hepatic and pulmonary lesions are common in cetaceans, despite their poorly understood viral etiology. Herpesviruses (HV), adenoviruses (AdV) and hepatitis E virus (HEV) are emerging agents in cetaceans, associated with liver and/or pulmonary damage in mammals. We isolated and molecularly tested DNA for HV and AdV (n = 218 individuals; 187 liver and 108 lung samples) and RNA for HEV (n = 147 animals; 147 liver samples) from six cetacean families. All animals stranded or were bycaught in Brazil between 2001 and 2021. Positive-animals were analyzed by histopathology. Statistical analyses assessed if the prevalence of viral infection could be associated with the variables: species, family, habitat, region, sex, and age group. All samples were negative for AdV and HEV. Overall, 8.7% (19/218) of the cetaceans were HV-positive (4.8% [9/187] liver and 11.1% [12/108] lung), without HV-associated lesions. HV-prevalence was statistically significant higher in Pontoporiidae (19.2%, 10/52) when compared to Delphinidae (4.1%, 5/121), and in southeastern (17.1%, 13/76)-the most industrialized Brazilian region-when compared to the northeastern region (2.4%, 3/126). This study broadens the herpesvirus host range in cetaceans, including its description in pygmy sperm whales (Kogia breviceps) and humpback whales (Megaptera novaeangliae). Further studies must elucidate herpesvirus drivers in cetaceans. (AU) | |
| Processo FAPESP: | 18/25069-7 - Estudo e caracterização de agentes virais emergentes selecionados e potencialmente associados a hepatopatias em cetáceos costeiros, pelágicos e de habitat misto no Brasil |
| Beneficiário: | Carlos Sacristan Yague |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 20/12434-9 - Pesquisa de infecções virais selecionadas e de genes de resistência bacteriana a antimicrobianos em mamíferos aquáticos no Brasil |
| Beneficiário: | Samira Costa da Silva |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 19/26794-0 - Estudo e caracterização de agentes virais emergentes selecionados e potencialmente associados a hepatopatias em cetáceos costeiros, pelágicos e de habitat misto no Brasil |
| Beneficiário: | Jose Luiz Catao Dias |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |