Autor(es)

Araujo, Jucara da Cruz ; de Oliveira, Danielle Carvalho Fonseca Falanga ; Souza, Leticia Gabrielle ; De Moraes, Augusto Cesar Ferreira ; de Oliveira, Ariclecio Cunha

• Tipo de documento: Artigo Científico
• Fonte: CHILDHOOD OBESITY; v. N/A, p. 10-pg., 2025-04-04.

Resumo

Background: The objective of this study was to test the association of Pro-Inflammatory/Anti-Inflammatory Food Intake Score (PAIFIS) and inflammatory biomarkers: C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 levels in a sample of Brazilian children.Methods: This cross-sectional study included children aged 5-8 years. Levels of inflammatory biomarkers and habitual food intake were measured using a quantitative food frequency questionnaire (FFQ) to estimate PAIFIS and anthropometric and socioeconomic data. The Mann-Whitney test, Spearman's correlation test, and nonparametric regression models with Kernel effects were used for analysis.Results: PAIFIS showed an association with increased TNF-alpha in the univariate analysis [beta = 0.53, 95% confidence interval (CI) 0.05-1.15] and the multivariate analysis adjusted for the sum of skinfolds (Sigma SF) and income (beta = 0.31, 95% CI 0.00-1.11). Sigma SF was associated with an increase in TNF-alpha (beta = 15.0, 95% CI 3.16-36.1) and CRP (beta = 0.013, 95% CI 0.004-0.022).Conclusions: The PAIFIS shows a positive association with TNF-alpha. Adiposity was also identified as an important risk factor for inflammation. (AU)

• Processo FAPESP: 17/20317-0 - Novas fronteiras em saúde nutricional e cardiovascular pediátrica: desenvolvimento de métodos para avaliar a dupla carga de má-nutrição e a saúde cardiovascular ideal em países de baixa-média renda - SAYCARE cohort study
• Beneficiário: Augusto César Ferreira de Moraes
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores