| Texto completo | |
| Autor(es): |
de Oliveira, Gabriela Fonseca
;
de Souza, Joao Carlos
;
da Silva, Jose Luiz
;
Zanoni, Maria Valnice Boldrin
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PROCESSES; v. 13, n. 5, p. 16-pg., 2025-04-25. |
| Resumo | |
Urea level determination in biological fluids provides nutritional information regarding the body metabolism and/or the renal condition. In order to propose a rapid determination of this biomarker at low levels in biological fluid samples, the present work developed an electrochemical sensor based on a simple arrangement of a nickel-nanoparticle-modified glassy carbon electrode (GCE/NiNPs). Under optimal conditions for selective urea detection, a linear response was obtained in the range of 0.085 to 3.10 mmol L-1 (R = 0.9993), with a limit of detection of 60.0 mu mol L-1 and limit of quantification of 198.0 mu mol L-1. The GCE/NiNPs sensor showed recovery rates from samples from 105 +/- 0.2% (hemodialysis wastewater) to 111 +/- 0.3% (dialysate) for urea determination in biological fluid samples. The results obtained showed that the proposed method is relatively easy to operate and has a good degree of reliability and the satisfactory sensitivity required for monitoring urea, as well as exhibiting excellent detection capacity in the presence of possible interferents in both samples. (AU) | |
| Processo FAPESP: | 14/50945-4 - INCT 2014: Instituto Nacional de Tecnologias Alternativas para Detecção, Avaliação Toxicológica e Remoção de Micropoluentes e Radioativos |
| Beneficiário: | Maria Valnice Boldrin |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 21/12866-9 - Desenvolvimento de sensores eletroquímicos utilizados na detecção eletroquímica de BTEXs em águas residuais de petróleo autoalimentados por uma célula a combustível microbiana: detecção de BTEXs, tratamento e produção de energia |
| Beneficiário: | João Carlos de Souza |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |