| Texto completo | |
| Autor(es): |
Orsi, Juan B.
;
Scariot, Pedro P. M.
;
Polisel, Emanuel E. C.
;
Araujo, Lara S.
;
Santos, Matheus R.
;
Papoti, Marcelo
;
Manchado-Gobatto, Fulvia B.
;
Gobatto, Claudio A.
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY; v. N/A, p. 14-pg., 2025-06-06. |
| Resumo | |
Researchers have extensively studied how hypoxia affects physiological variables, with training models like "live high - train low" (LH-TL) proposed by Levine & Stray-Gundersen in 1997 to improve athletic performance. Although well-known, few studies use animal models for more in-depth analyses than human studies allow. This study investigated the effects of aerobic training on adiposity, spontaneous physical activity (SPA), and food and water intake in C57BL/6J mice housed in normoxic (Nx) or hypoxic (Hx) conditions for 8 weeks. Mice were divided into trained (T) and sedentary (S) groups, with 10 mice each. Hx animals were kept in normobaric hypoxia (FiO2=14.5%) for 18 h/day. Training was done at 80% critical velocity, 5 times/week in normoxia. The T groups had lower SPA, especially the Hx-T group, which showed higher food and water intake, reduced fat, and a higher fat-free mass/carcass fat mass ratio. Findings suggest exercise and hypoxia may help combat obesity. (AU) | |
| Processo FAPESP: | 24/04688-1 - Efeitos do modelo de treinamento "viver alto - treinar baixo" sobre respostas hematimétricas, biomoleculares e bioquímicas associadas ao balanço energético |
| Beneficiário: | Juan Bordon Orsi |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado Direto |
| Processo FAPESP: | 19/05115-7 - Efeitos do treinamento aeróbio e do ambiente em hipóxia sobre respostas moleculares envolvidas com o metabolismo anaeróbio, aeróbio e controle ácido-básico nos tecidos hipotalâmico e muscular de camundongos |
| Beneficiário: | Pedro Paulo Menezes Scariot |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 17/10201-4 - Efeitos do treinamento físico aeróbio e espaço habitacional de camundongos sobre a atividade física espontânea e respostas metabólicas e moleculares centrais e periféricas. |
| Beneficiário: | Claudio Alexandre Gobatto |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |