| Texto completo | |
| Autor(es): |
Paixao, Douglas B.
;
Seckler, Diego
;
Gomes, Carla M. B.
;
Badshah, Gul
;
Bueno, Gabriel P.
;
Schneider, Paulo H.
;
Schwab, Ricardo S.
;
Rampon, Daniel S.
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; v. 28, n. 20, p. 27-pg., 2025-05-02. |
| Resumo | |
The transition metal-catalyzed direct C-S and C-Se bond formation from C-H bonds has emerged as an efficient synthetic strategy for constructing previously inaccessible organochalcogen compounds, opening a new gateway to late-stage functionalization of pharmaceutical-relevant molecules and organic functional materials. C-Y bonds (Y=S, Se, Te) also show outstanding strategic relevance as handles to access other valuable functional groups downstream in a synthetic route. Despite the significant progress, the chemo-, site-, and enantioselective C-S and C-Se bond formation from unactivated Csp(3)-H bonds is still challenging owing to its low polarity and inertness. Here, a comprehensive overview of the transition metal-catalyzed direct conversion of unactivated Csp(3)-H to C-S and C-Se bonds in the last decade is provided, looking to motivate the continuous discovery of innovative and efficient systems for these transformations. (AU) | |
| Processo FAPESP: | 21/12394-0 - Métodos sintéticos sustentáveis empregando catálise, solventes verdes, reagentes seguros e materiais de partida renováveis |
| Beneficiário: | Arlene Gonçalves Corrêa |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 13/06558-3 - Catálise metálica assimétrica: preparação de alcoóis quirais e seus derivados a partir de reagentes orgânicos de zinco poli-funcionalizados e aplicação de novos ligantes quirais suportados em nanopartículas magnéticas |
| Beneficiário: | Ricardo Samuel Schwab |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |