| Texto completo | |
| Autor(es): Mostrar menos - |
Matsuda, Renan H.
;
Souza, Victor H.
;
Marchetti, Thais C.
;
Soto, Ana M.
;
Kahilakoski, Olli-Pekka
;
Laine, Mikael
;
Sinisalo, Heikki
;
Kicic, Dubravko
;
Lioumis, Pantelis
;
Ilmoniemi, Risto J.
;
Baffa, Oswaldo
Número total de Autores: 11
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Physics in Medicine and Biology; v. 70, n. 16, p. 11-pg., 2025-08-17. |
| Resumo | |
Background. Multi-locus TMS (mTMS) enables precise electronic control of brain stimulation targeting, eliminating the need for physical coil movement. However, with a small number of coils, the stimulation area is constrained, and manual handling of the coil array is cumbersome. Combining electronic mTMS targeting with robotics enables automated, user-independent, and precise brain stimulation protocols. Objective. To characterize an open-source electronic-robotic mTMS platform for rapid and accurate brain stimulation targeting. Methods. We developed an automated robotic mTMS positioning platform. We used a 5-coil mTMS device coupled to a collaborative robot. The stimulation targeting accuracy of the system was quantified with a TMS characterizer that measures the TMS-induced electric field (E-field) on a model of a spherical cortex. The induced E-field distortion generated by robot coupling was evaluated for each coil. We compared the repositioning accuracy of robotic-electronic system to the conventional manual positioning. Results. Our collaborative-robot-based system offers submillimeter precision and autonomy in positioning mTMS coil sets. The electronic-robotic mTMS platform was approximately 1.8 mm and 1.0 degrees more accurate than the conventional manual positioning. Integrating robotics and mTMS automates brain stimulation procedures, resulting in minimal reliance on user expertise and subjective analysis. Conclusion. Our open-source platform combining rapid mTMS targeting with robotic precision enhances the safety and reproducibility of TMS, enabling more efficient and reliable outcomes than previous techniques. (AU) | |
| Processo FAPESP: | 13/07699-0 - Centro de Pesquisa, Inovação e Difusão em Neuromatemática - NeuroMat |
| Beneficiário: | Oswaldo Baffa Filho |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |
| Processo FAPESP: | 22/15500-8 - Desenvolvimento e validação de um método de determinação do hotspot para estimulação magnética transcraniana baseada em tractografia através do posicionamento robótico |
| Beneficiário: | Thais Cunha Marchetti |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 22/14526-3 - Um modelo de árvore de contexto pode prever a excitabilidade do córtex motor primário? Um estudo de estimulação magnética transcraniana robotizada navegada por eletromiografia e eletroencefalografia. |
| Beneficiário: | Renan Hiroshi Matsuda |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |