| Texto completo | |
| Autor(es): Mostrar menos - |
Pingueiro, Joao Marcos Spessoto
;
Feres, Magda
;
Macedo, Tatiane Tiemi
;
Paulo Gomes, Aline Paim de Abreu
;
Vilela, Felipe Mazzini Silva
;
Bueno, Manuela Rocha
;
da Silva, Lucas Daylor Aguiar
;
Silva, Anna Paula de Souza
;
Alencar, Severino Matias
;
Rosalen, Pedro Luiz
;
Bueno-Silva, Bruno
Número total de Autores: 11
|
| Tipo de documento: | Artigo Científico |
| Fonte: | BIOFOULING; v. 41, n. 9, p. 11-pg., 2025-08-28. |
| Resumo | |
The aim of this study was to evaluate effects of neovestitol-vestitol fraction (NVF) on an in vitro subgingival multispecies biofilm. The 33-species biofilm was formed for seven days using a Calgary device. Starting on day 3, treatments for applied twice daily for 1 min each: NV (400-1,600 mu g ml(-1)), chlorhexidine 0.12% (CHX; positive control) or vehicle (negative control). After seven days, metabolic activity and microbial composition were accessed through colorimetric reaction and DNA-DNA hybridization, respectively. ANOVA/Tukey's and Kruskal-Wallis/Dunn's were performed (p < 0.05). NV1,600 and NV800 and CHX significantly reduced biofilm metabolic activity by 67%, 48% and 64% respectively, compared to vehicle-treatment. NV1,600, NV800 and CHX reduced red complex proportions versus vehicle-treatment. NV1,600 also reduced orange complex and increased healthy-associated purple complex compared to negative control (p < 0.05). NV1,600, NV800 and CHX reduced nine species, including Fusobacterium periodonticum and Porphyromonas gingivalis. NV1,600 also reduced Fusobacterium nucleatum polymorphum. NV seems to be a good candidate to control biofilm formation and pathogenicity in dental practice. (AU) | |
| Processo FAPESP: | 17/16377-7 - Avaliação do efeito de bactérias probióticas sobre a resposta imune contra a.actinomycetemcomitans: estudo em células epiteliais gengivais e em modelo experimental de infecção in vivo. |
| Beneficiário: | Manuela Rocha Bueno |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 19/19691-0 - Atividade de compostos bioativos da própolis vermelha brasileira sobre a doença periodontal |
| Beneficiário: | Bruno Bueno Silva |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |