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Effects of Carbon-Based and Organic Nanoparticles in Advanced Dressings for Skin Regeneration: A Review

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Autor(es):
Rodrigues, Karla Faquine ; de Oliveira, Thais Cardoso ; Montanheiro, Thais Larissa do Amaral ; Kito, Leticia Terumi ; Schatkoski, Vanessa Modelski ; dos Santos, Alan Silva ; Pereira, Raissa Monteiro ; Boccaccini, Aldo Roberto ; Thim, Gilmar Patrocinio ; Unalan, Irem
Número total de Autores: 10
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL WOUND JOURNAL; v. 22, n. 7, p. 16-pg., 2025-07-01.
Resumo

Chronic wounds may develop when there is a delay or disturbance in one of the stages of the healing process, presenting challenging financial, clinical, and quality-of-life costs. Therefore, continuous efforts have been made to develop dressings that optimise wound healing. In recent years, nanotechnology has revolutionised wound care, enabling the development of innovative materials with high efficiency that positively impact the healing process. Nanoparticles have been extensively used in wound dressings because of their specific properties, such as a high surface area-to-volume ratio, increased surface reactivity, and improved biocompatibility, representing a unique tissue repair tool. This review article addresses advances in the use of organic nanoparticles in the field of skin regeneration, considering papers published in the last 5 years, and highlighting the effects of this class of materials on the wound healing process. The analysis of the literature shows that the materials being considered are carbon-based and organic materials, including polymeric, cellulosic, lipid, and liposome nanoparticles, which are covered in this review (inorganic nanoparticles are not considered). Furthermore, important aspects to prevent the development of chronic wounds are presented, as well as general characteristics of wounds, the healing process, and their particularities. (AU)

Processo FAPESP: 19/05856-7 - Aplicações de plasmas atmosféricos não-térmicos na odontologia: da bancada para a clínica
Beneficiário:Cristiane Yumi Koga Ito
Modalidade de apoio: Auxílio à Pesquisa - Temático
Processo FAPESP: 21/09335-1 - Nanofibras eletrofiadas à base de policaprolactona, nanocristais de celulose e óleo essencial de Melaleuca alternifolia para regeneração tecidual
Beneficiário:Karla Faquine Rodrigues
Modalidade de apoio: Bolsas no Brasil - Doutorado