| Texto completo | |
| Autor(es): |
Martinez-Ramirez, Josefina
;
Brandao, Thais Bianca
;
Bonfim Alves, Carolina Guimaraes
;
Rodrigues-oliveira, Leticia
;
Kowalski, Luiz Paulo
;
Toporcov, Tatiana Natasha
;
Santos-silva, Alan Roger
;
Ribeiro, Ana Carolina Prado
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ORAL DISEASES; v. N/A, p. 9-pg., 2025-12-26. |
| Resumo | |
Objective To estimate the time intervals from first symptom to treatment initiation and to explore the multifaceted challenges faced by patients with oral cavity and oropharynx squamous cell carcinoma (OCSCC and OPSCC) during their diagnostic journey.Methods A cross-sectional study was conducted with 182 patients diagnosed with OCSCC or OPSCC admitted at the S & atilde;o Paulo State Cancer Institute between January 2019 and November 2020. The patient interval (PI), health system diagnostic interval (HSDI), and pretreatment interval (PTI) were evaluated.Results Most patients were diagnosed at stage T3/T4 for both OCSCC (74.1%) and OPSCC (77.4%). The median PI was 1 month (IQR: 0-3), the median HSDI was 3 months (IQR: 2-6), and the median PTI was 3 months (IQR: 2-4). Patients with p16-positive OPSCC were slightly more likely to experience a longer PI (IRR = 2.38; 95% CI: 1.00-5.67; p = 0.0499). The number of healthcare services visited showed the strongest association with progressively increased HSDI.Conclusions Sociodemographic and clinical factors were associated with variations in the duration of the interval from symptom onset to treatment initiation. Targeted interventions to streamline referral pathways, strengthen professional training, and increase awareness among high-risk populations could substantially improve timeliness of care and patient outcomes. (AU) | |
| Processo FAPESP: | 24/20694-1 - Desenvolvimento de um Programa de Rastreamento de Desordens Orais Potencialmente Malignas e Carcinoma Espinocelular de Cavidade Oral na América Latina e Caribe. |
| Beneficiário: | Alan Roger dos Santos Silva |
| Modalidade de apoio: | Bolsas no Exterior - Pesquisa |