Bouts of passive stretching after immobilization of the rat soleus muscle increase collagen macromolecular organization and muscle fiber area

Autor(es)

Coutinho‚ E.L. ; DeLuca‚ C. ; Salvini‚ T.F. ; Vidal‚ B.C.

• Tipo de documento: Artigo Científico
• Fonte: Connective Tissue Research; v. 47, n. 5, p. 278-286, 2006.

Resumo

This study evaluated the effect of short bouts of stretching on the soleus muscle after immobilization, by measuring the birefringence of the intramuscular connective tissue (ICT) and the muscle fiber area. Thirty rats were divided into five groups: the left soleus was immobilized in the shortened position; after immobilization the animals remained free; after immobilization, the soleus was stretched daily (10 stretches of 60 sec followed by 30 sec rest); after immobilization, the soleus was stretched 3 times a week; control. Immobilization caused a loss of birefringence of the ICT and of muscle fiber area and only daily stretching increased both compared with the control (p < 0.01). In conclusion, short daily bouts of stretching after immobilization induced molecular reorganization of the collagen bundles and muscle fiber hypertrophy in the rat soleus. (AU)

• Processo FAPESP: 03/04597-0 - Ordem molecular e organização supramolecular em feixes de colágeno: diferenças com a funcionalidade, como suposto efeito de expressão de patogenia, e contribuição metodológica
• Beneficiário: Benedicto de Campos Vidal
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 03/10889-3 - O efeito do alongamento muscular na expressao genica dos fatores regulatorios miogenicos (mrfs).
• Beneficiário: Tania de Fatima Salvini
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 01/13523-4 - O efeito de sessoes periodicas de alongamento passivo no musculo esqueletico encurtado.
• Beneficiário: Tania de Fatima Salvini
• Modalidade de apoio: Auxílio à Pesquisa - Regular