EROD activity and genotoxicity in the seabob shrimp Xiphopenaeus kroyeri exposed to benzo[a]pyrene (BaP) concentrations

Autor(es)

da Silva Rocha, Arthur Jose ^[1] ; Gomes, Vicente ^[1] ; Campos Rocha Passos, Maria Jose de Arruda ^[1] ; Hasue, Fabio Matsu ^[1] ; Alves Santos, Thais Cruz ^[1] ; Bicego, Marcia Caruso ^[2] ; Taniguchi, Satie ^[2] ; Ngan, Phan Van ^[3]

Afiliação do(s) autor(es)

^[1] Lab Ecofisiol Anim Marinhos, Dept Oceanog Biol, Inst Oceanog, BR-05508900 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Lab Quim Organ Marinha LABQOM, Dept Oceanog Fis, Inst Oceanog, BR-05508900 Sao Paulo - Brazil

^[3] Phan Van Ngan, Univ Sao Paulo, Lab Ecofisiol Anim Marinhos, Dept Oceanog Biol, Inst Oceanog, BR-05508900 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 34, n. 3, p. 995-1003, NOV 2012.
• Citações Web of Science: 15

Resumo

Seabob shrimp Xiphopenaeus kroyeri is a marine species that lives in shallow waters of coastal environments, often impacted by polycyclic aromatic hydrocarbons (PAH) pollution. In the present study, seabob shrimp were exposed for 96 h to benzo{[}a]pyrene (BaP) at the nominal concentrations of 100, 200, 400 and 800 microg.L-1. Animals of the control groups were exposed either to clean water or to the BaP-carrier (DMSO). At the end of the exposures, muscle tissues were sampled for BaP uptake assessment and hepatopancreas and hemolymph for EROD enzyme activity and hemocytes DNA damage, respectively. EROD activity and DNA damage increased significantly as a function of BaP exposure concentrations. Significant correlations between BaP uptake and both EROD activity and DNA damage suggest that they can be used as suitable tools for integrated levels of study on the biomarkers of PAH exposure. (C) 2012 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 06/03925-1 - Estudo sobre a genotoxicidade do hidrocarboneto policíclico aromático (HPA) benzo [a]pireno na cadeia alimentar: relação presa-predador
• Beneficiário: Arthur José da Silva Rocha
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 07/01012-1 - Estudo sobre a genotoxicidade do hidrocarboneto policiclico aromático (HPA) benzo[a]pireno na cadeia alimentar: relação presa predador
• Beneficiário: Phan van Ngan
• Modalidade de apoio: Auxílio à Pesquisa - Regular