| Texto completo | |
| Autor(es): |
Rita de Cássia de Lima Sampaio
[1]
;
Julio Carlos Canola
[2]
;
José Corrêa de Lacerda Neto
[3]
;
Julieta Rodini Engrácia de Moraes
[4]
Número total de Autores: 4
|
| Afiliação do(s) autor(es): | [1] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[2] UNESP. FCAV. Departamento de Patologia Veterinária - Brasil
[3] UNESP. Departamento de Clínica e Cirurgia Veterinária - Brasil
[4] UNESP. FCAV. Departamento de Patologia Veterinária - Brasil
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INTERNATIONAL JOURNAL OF MORPHOLOGY; v. 22, n. 4, p. 307-312, 2004-12-00. |
| Resumo | |
The morphological characteristics of the hooves of two groups of horses were studied. The first group was comprised of six adult animals without any treatment and served as the control. The other group, comprised of seven horses, received carbohydrates overload orally. Of these, 71% developed laminitis between 36 and 48 hours after carbohydrate administration. After 48 hours of induction, the animals were sacrificed and their fore limbs and hindlimbs were removed for histologic study. Tissue sections 5 to 7 µm thick were obtained, stained with hematoxylin-eosin (H&E) or periodic acid Schiff's (PAS), and then examined by light microscopy. It was possible to identify in horses from the laminitis group, morphological and structural changes in the architecture of the primary and secondary epidermal lamellae, which were found to be sharpened and elongated with basal cells having round-shaped nuclei and also localized at the basal pole. PAS staining showed that in horses from the control group there were the presence of a basement membrane, separating and outlining the dermal and epidermal lamellae. In the laminitis group horses, there were deformation and fragmentation of the basement membrane. The utilization of PAS permitted the determination of the degenerative alterations in the basement membrane, which occurred early and coincident with the development of clinical signs of lameness (AU) | |
| Processo FAPESP: | 00/10308-2 - Estudo clínico e histopatológico da ação de precursores de óxido nítrico na fase prodrômica da laminite de equinos |
| Beneficiário: | José Corrêa de Lacerda Neto |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |