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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Multifunctional luminomagnetic FePt@Fe3O4/SiO2/Rhodamine B/SiO2 nanoparticles with high magnetic emanation for biomedical applications

Texto completo
Souza, C. G. S. [1] ; Beck, Jr., W. [1] ; Varanda, L. C. [1]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Quim Sao Carlos, Colloidal Mat Grp, BR-13566590 Sao Carlos, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Citações Web of Science: 7

Multifunctional luminomagnetic nanoparticles with average particle diameter around 34 nm and enhanced magnetic properties are reported. FePt@Fe3O4 magnetic nuclei with 6.0 +/- 0.7 nm in a core-shell nanostructure were synthesized combining the modified polyol and seed-mediated growth processes, coated with silica by reverse micelle route and annealed. Individual silica-coated magnetic core resulted in a mixture of hard and soft magnetic nanostructured material with superparamagnetic behavior and enhanced magnetic emanation. Luminescent dye Rhodamine B (RhB) was incorporated onto the nanoparticle surface followed by coating with an outer silica shell in a layer-by-layer structure. The bifunctional luminomagnetic nanoparticles of FePt@Fe3O4/SiO2/RhB/SiO2 present high-water dispersibility, colloidal stability, and hydrophilic surface with isoelectric point of 2.7. The superparamagnetic behavior was preserved with blocking temperature of 40 K and the saturation magnetization of the final product equal 64.3 emu g(-1) was around ten times higher than observed for nanoparticles using pure magnetite core synthesized in the same conditions. Inner and outer silica layers minimize luminescence quenching processes due to avoid contact between dye and both magnetic core and solvent, respectively, resulting in a stable emission for, at least, 1 h. These properties allied with the possibility to use different dye compounds gives a potential bifunctional nanosensor for biomedical applications. (AU)

Processo FAPESP: 07/07919-9 - Nanocristais magnéticos coloidais: obtenção de nanoesferas, nanofios e nanobastões auto-organizados e funcionalizados com macromoléculas para aplicação em gravação magnética avançada, biotecnologia e biomedicina
Beneficiário:Laudemir Carlos Varanda
Linha de fomento: Auxílio à Pesquisa - Apoio a Jovens Pesquisadores