Study of some volatile compounds evolved from the thermal decomposition of atenolol

Autor(es)

Silva, A. C. M. ^[1] ; Galico, D. A. ^[1] ; Guerra, R. B. ^[1] ; Legendre, A. O. ^[1] ; Rinaldo, D. ^[1] ; Galhiane, M. S. ^[1] ; Bannach, G. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, Fac Ciencias, Dept Quim, UNESP, BR-17033260 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY; v. 115, n. 3, p. 2517-2520, MAR 2014.
• Citações Web of Science: 9

Resumo

Simultaneous thermogravimetry-differential scanning calorimetry (TG-DSC) and coupled thermogravimetry-infrared spectroscopy (TG-FTIR) analyses were used to study the antihypertensive drug atenolol. The TG-DSC curves provided information concerning the thermal stability and decomposition profiles of the compound. From the TG-FTIR coupled techniques, it was possible to identify ammonia and isopropylamine as possible volatile compounds released during the thermal decomposition of the drug. (AU)

• Processo FAPESP: 12/21450-1 - Estudos termoanalíticos, síntese e caracterização dos co-cristais sólidos de cetoprofeno com alguns co-formadores
• Beneficiário: Gilbert Bannach
• Modalidade de apoio: Auxílio à Pesquisa - Regular