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PROCESS FOR PRODUCING A HYBRID SYSTEM, HYBRID SYSTEM AND USE THEREOF

Document type:Patente
Inventor(s): Nelson Eduardo Durán Caballero; Letícia Montanholi Apolinário; Wagner José Fávaro; Amauri Jardim de Paula; Camila Pedroso Silveira Bueno
Applicant: Universidade Estadual de Campinas (UNICAMP)
Deposit date: May 2015, 15
INPI register:
PCT/BR2015/000069 - INPI Search
IPC: A61P 35/00 A61K 47/30 A61K 47/02 B82Y 5/00 A61K 9/51 A61K 31/519 A61K 31/704
Abstract

The present invention provides a process for producing a hybrid system containing a biocompatible polymer hydrogel and mesoporous silica nanoparticles incorporating drugs, as well as the hybrid system and use thereof for anti-tumour treatment. More specifically, the hybrid system of the present invention comprises doxorubicin (DOX) and/or sildenafil as drugs incorporated in the pores of the nanoparticles, with the aim of producing novel material for anti-tumour treatment, especially for treating prostate cancer.


FAPESP's process: 12/08677-7 - Design of hybrid systems based on porous silica and alginate for medical applications
Grantee:Amauri Jardim de Paula
Principal researcher:Nelson Eduardo Duran Caballero
Institution: Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ)
Support type: Scholarships in Brazil - Post-Doctorate