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PROCESS FOR PRODUCING A HYBRID SYSTEM, HYBRID SYSTEM AND USE THEREOF
| Document type: | Patente |
| Inventor(s): | Nelson Eduardo Durán Caballero; Letícia Montanholi Apolinário; Wagner José Fávaro; Amauri Jardim de Paula; Camila Pedroso Silveira Bueno |
| Applicant: | Universidade Estadual de Campinas (UNICAMP) |
| Deposit date: | May 2015, 15 |
| INPI register: | |
| IPC: | A61P 35/00 A61K 47/30 A61K 47/02 B82Y 5/00 A61K 9/51 A61K 31/519 A61K 31/704 |
Abstract
The present invention provides a process for producing a hybrid system containing a biocompatible polymer hydrogel and mesoporous silica nanoparticles incorporating drugs, as well as the hybrid system and use thereof for anti-tumour treatment. More specifically, the hybrid system of the present invention comprises doxorubicin (DOX) and/or sildenafil as drugs incorporated in the pores of the nanoparticles, with the aim of producing novel material for anti-tumour treatment, especially for treating prostate cancer.
| FAPESP's process: | 12/08677-7 - Design of hybrid systems based on porous silica and alginate for medical applications |
| Grantee: | Amauri Jardim de Paula |
| Principal researcher: | Nelson Eduardo Duran Caballero |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) |
| Support type: | Scholarships in Brazil - Post-Doctorate |