Fabrication and characterization of peptide-polymer hybrid hydrogels for bioanalytical applications

• Processo: 16/50188-4
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Data de Início da vigência: 01 de setembro de 2016
• Data de Término da vigência: 31 de outubro de 2018
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Acordo de Cooperação: University of Melbourne
• Proposta de Mobilidade: SPRINT - Projetos de pesquisa - Mobilidade
• Pesquisador responsável: Wendel Andrade Alves
• Beneficiário: Wendel Andrade Alves
• Pesquisador Responsável no exterior: Francesca Cavalieri
• Instituição Parceira no exterior: University of Melbourne, Austrália
• Instituição Sede: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brasil
• Vinculado ao auxílio: 15/24018-1 - Conjugados polímero-peptídeo para formulação de hidrogéis e seu uso em detecção, AP.R
• Assunto(s): Métodos bioanalíticos Técnicas e procedimentos diagnósticos Leishmaniose Materiais nanoestruturados Hidrogéis
• Palavra(s)-Chave do Pesquisador: Quimica

Resumo

The objective of this research project is to promote an exchange program between UoM and UFABC. The proposed joint project is set to enhance educational/research scientific excellence in the two universities. This will ultimately help in securing large grants from other organizations for continuing our collaborative research activities for the long-term. The achievement of this goal requires an interdisciplinary approach based on complementary expertise of the two participants in peptide self-assembly and polymeric hydrogels. The outcome of this collaborative project will yield high quality publications and breakthrough for rapid diagnostic of leishmaniosis and other diseases endemic in tropical countries. The objective of this research/exchange project is to fabricate a new biosensor based on peptidepolymer hydrogels for the detection of leishmaniosis and other diseases endemic in tropical countries. The achievement of this goal requires an interdisciplinary approach based on complementary expertise of the two participants. Prof. Alves is an expert in peptide synthesis and self-assembly into nanostructures whereas Dr. Cavalieri has consolidated skins on the engineering and characterization of polymer based hydrogels for biomedical applications. The proposed joint research project aligns well with the ongoing research of the participants and meantime increases skills and knowledge of both applicants. (AU)

Publicações científicas

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

GERBELLI, BARBARA B.; VASSILIADES, SANDRA V.; ROJAS, JOSE E. U.; PELIN, JULIANE N. B. D.; MANCINI, RODRIGO S. N.; PEREIRA, WALLACE S. G.; AGUILAR, ANDREA M.; VENANZI, MARIANO; CAVALIERI, FRANCESCA; GIUNTINI, FRANCESCA; et al. Hierarchical Self-Assembly of Peptides and its Applications in Bionanotechnology. MACROMOLECULAR CHEMISTRY AND PHYSICS, v. 220, n. 14, p. 22-pg., 2019-07-01. (18/05888-3, 17/02317-2, 14/50867-3, 16/50188-4, 14/50972-1)

GERBELLI, BARBARA B.; VASSILIADES, SANDRA V.; ROJAS, JOSE E. U.; PELIN, JULIANE N. B. D.; MANCINI, RODRIGO S. N.; PEREIRA, WALLACE S. G.; AGUILAR, ANDREA M.; VENANZI, MARIANO; CAVALIERI, FRANCESCA; GIUNTINI, FRANCESCA; et al. Hierarchical Self-Assembly of Peptides and its Applications in Bionanotechnology. MACROMOLECULAR CHEMISTRY AND PHYSICS, v. 220, n. 14, SI, JUL 2019. (18/05888-3, 16/50188-4, 17/02317-2, 14/50972-1, 14/50867-3)

LIBERATO, MICHELLE S.; MANCINI, RODRIGO S. N.; FACTORI, IRINA M.; FERREIRA, FABIO F.; DE OLIVEIRA, VIVIAN L.; CARNIELLI, JULIANA B. T.; GUHA, SUCHISMITA; PERONI, LUIS A.; OLIVEIRA, MARCONE A. L.; ALVES, WENDEL A.. Peptide-Based Assemblies on Electrospun Polyamide-6/Chitosan Nanofibers for Detecting Visceral Leishmaniasis Antibodies. ACS APPLIED ELECTRONIC MATERIALS, v. 1, n. 10, p. 2086-2095, OCT 2019. (14/50867-3, 17/02317-2, 16/50188-4)