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METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES
| Tipo de documento: | Patente |
| Inventor(es): | José Agustín Quincoces Suárez; Durvanei Augusto Maria; Daniela Goncales Rando; Paulo Celso Pardi |
| Depositante: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) |
| Data do depósito: | 06 de julho de 2006 |
| Registro INPI: | |
| IPC: | C07C 49/603 C07C 45/74 A61K 31/121 |
Resumo
The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition consisting of the referred compounds, method of treatment for cancer and parasitic diseases.
| Processo FAPESP: | 01/10383-7 - Propriedades antitumorais da 1,5-bis(4-hidroxi-3-methoxi-fenil) penta-1,4-dien-3-ona e seus derivados |
| Beneficiário: | José Agustín Pablo Quincoces Suárez |
| Pesquisador responsável: | José Agustín Pablo Quincoces Suárez |
| Instituição: | Universidade Bandeirantes (UNIBAN). Pró-Reitoria Acadêmica |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa de Apoio à Propriedade Intelectual (PAPI/Nuplitec) |