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METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES

Document type:Patente
Inventor(s): José Agustín Quincoces Suárez; Durvanei Augusto Maria; Daniela Goncales Rando; Paulo Celso Pardi
Applicant: Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Deposit date: July 2006, 06
INPI register:
PCT/BR2007/000175
IPC: C07C 49/603 C07C 45/74 A61K 31/121
Abstract

The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition consisting of the referred compounds, method of treatment for cancer and parasitic diseases.


Grantee:José Agustín Pablo Quincoces Suárez
Principal Investigator:José Agustín Pablo Quincoces Suárez
Institution: Universidade Bandeirantes (UNIBAN). Pró-Reitoria Acadêmica
Support Opportunities: Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec)