Abstract
Ovarian cancer (OvCa) is the leading cause of death from gynecological malignancies, with high-grade serous ovarian carcinoma (HGSOC) being the most lethal subtype. Characterized by mutations in TP53, BRCA1/2, and other genes, it exhibits high molecular heterogeneity and is strongly influenced by the tumor microenvironment. This perfil affects prognosis, therapeutic response, and diagnost…
