FAPESP Regular Grants support research to be developed under the responsibility of a Principal Investigator, associated with higher education or research institutions in the State of São Paulo. The maximum duration of a Regular Research Grant is 2 years and selection is through a peer-reviewing system.
The detection of a stimulus or stressor that can disrupt homeostasis is essential for the protection of the organism. Thus, the presence of various neurocircuits/pathways related to the detection of similar stimuli ensures redundancy in the system, facilitating effective identification of risks to the organism's integrity. Hypothalamic neurons in the paraventricular nucleus (PVN) that pro…
Polycystic ovary syndrome (PCOS) and early (<10 years) or late (¿16 years) age at menarche represent endocrine-reproductive phenotypes associated with an increased risk of adverse metabolic, reproductive, and cardiovascular outcomes in adulthood. These extreme pubertal timing phenotypes have been linked to neuroendocrine and metabolic alterations and share physiological, epidemiological, …
Effective resource management in emergency departments is essential for optimizing triage, early diagnosis, and accurate patient allocation, particularly in cases of pneumonia, which ranks among the leading causes of death globally and in Brazil. While clinical-laboratory scores such as CURB-65 and the Pneumonia Severity Index (PSI) are accurate for prognostic stratification, their use is…
(Only some records are available in English at this moment)
Microplastics and nanoplastics (MNPs) are ubiquitous environmental contaminants, and while their presence in human lung tissue has been confirmed, understanding of their atmospheric occurrence and the health risks associated with inhalation exposure remains scarce. To better assess these risks and overcome the limitations of animal models and traditional submerged cell cultures, air-liqui…
Sedation is an essential tool in the management of mechanically ventilated patients in Intensive Care Units (ICUs). Deep sedation is associated with worse outcomes, such as prolonged mechanical ventilation, delirium, and increased mortality. Current guidelines emphasize light and individualized sedation, preferably with non-benzodiazepine agents and daily awakening trials. However, during…
Compact objects, such as neutron stars, black holes, and white dwarfs, represent extreme physical environments in which gravity, magnetic fields, and matter density reach unexplored limits. The enigmatic Fast Radio Bursts (FRBs) phenomena, usually associated with these compact objects, stand out for their short duration, high energy, and poorly understood origin. This project proposes a s…
(Only some records are available in English at this moment)
Latent thermal energy storage systems are more efficient due to the utilization of latent heat. Some of the systems that have been proposed include the use of phase change materials (PCMs). PCMs absorb energy when the melting temperature is reached and release the absorbed energy when there is no more supply. These materials are also used for thermal control of electronic devices, solar e…
Introduction: The object of study in this research is the evaluation of the teaching-learning process in theoretical and theoretical-practical disciplines in Technical Vocational Education in Nursing (EPTNME) in São Paulo. To understand this issue, it is necessary to examine the context of EPTNME in Brazil, considering its theoretical-ideological, political, and technical influences on pe…
The collaboration aims to explore synergies between teams with experiences in a wide range of soil sensing techniques, both proximal and remote devices. The focus of this first year of collaboration will be on evaluating attributes related to soil chemical fertility, using chemical quality indices for the spatial distribution of individual attributes and their combined use to create soil …
(Only some records are available in English at this moment)
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