In Vitro Antimicrobial Activity of an Experimental Dentifrice Based on Ricinus Communis

Autor(es)

Vanessa Maria Fagundes Leite ^[1] ; Juliana Barchelli Pinheiro ^[2] ; Marina Xavier Pisani ^[3] ; Evandro Watanabe ^[4] ; Raphael Freitas de Souza ^[5] ; Helena de Freitas Oliveira Paranhos ^[6] ; Cláudia Helena Lovato-Silva ^[7]

Afiliação do(s) autor(es)

^[1] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

^[2] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

^[3] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

^[4] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Restorative Dentistry - Brasil

^[5] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

^[6] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

^[7] University of São Paulo. School of Dentistry of Ribeirão Preto. Department of Dental Materials and Prosthesis - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Brazilian Dental Journal; v. 25, n. 3, p. 191-196, 2014-07-00.

Resumo

This study evaluated the antimicrobial activity of a Ricinus communis-based experimental dentifrice for denture hygiene against the following standard strains: Staphylococcus aureus, Escherichia coli, Streptococcus mutans, Enterococcus faecalis, Candida albicans and Candida glabrata. The minimum inhibitory concentration (MIC) assay was performed with R. communis in pure oil at 2.5%. Only E. coli was not inhibited by R. communis, but the MIC (0.0781%) was effective against the other microorganisms. From these results it was determined the R. communis concentrations for experimental dentifrices, 1, 2, 5 and 10%, which were evaluated by the test-well diffusion in agar. The commercial dentifrices Colgate, Trihydral and Corega Brite were tested for comparative purposes. The diameter of the zones of bacterial growth inhibition produced around the wells was measured (in mm) with a rule under reflected light. Data were analyzed statistically by analysis of variance and Tukey's post-hoc test (α=0.05). Neither the commercial nor the experimental dentifrices were effective against E. coli. The experimental dentifrices containing R. communis at 2, 5 and 10% presented action against S. mutans, S. aureaus and E. faecallis. The experimental dentifrices showed no antimicrobial activity against Candida spp. and E. coli in any of the tested concentrations. Trihydral was the most effective. Comparing the experimental dentifrices, the product with 10% R. communis produced the largest zones of bacterial growth inhibition and had similar antimicrobial activity to the commercial dentifrices, except against S. aureus. (AU)

• Processo FAPESP: 10/50819-8 - Avaliação da ação antimicrobiana de um dentifrício experimental a base de Ricinus communis para higiene de prótese totais
• Beneficiário: Cláudia Helena Lovato da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular