Connective tissue graft as a biological barrier for guided tissue regeneration in intrabony defects: a histological study in dogs

Autor(es)

Ribeiro, Fernando Salimon ^[1] ; Farias Pontes, Ana Emilia ^[1] ; Zuza, Elizangela Partata ^[1] ; da Silva, Vanessa Camila ^[2] ; Comelli Lia, Raphael Carlos ^[1] ; Marcantonio Junior, Elcio ^[3]

Afiliação do(s) autor(es)

^[1] Educ Fdn Barretos UNIFEB, Sch Dent, Dept Master Dent Sci, BR-14783226 Barretos, SP - Brazil

^[2] Fed Univ Maranhao UFMA, Sch Dent, Dept Dent 2, Maranhao, MA - Brazil

^[3] Sao Paulo State Univ UNESP, Sch Dent, Dept Diag & Surg, Araraquara, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL ORAL INVESTIGATIONS; v. 19, n. 5, p. 997-1004, JUN 2015.
• Citações Web of Science: 0

Resumo

Background The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane. Methods Three-walled intrabony defects were created surgically in the mesial aspect of the right and left maxillary canines in five healthy mongrel dogs. The defects were chronified, and two types of barriers were randomly carried out for guided tissue regeneration in a split-mouth design: the test group with a subepithelial connective tissue graft and the control group with a bioabsorbable membrane. The specimens were processed for histometric analyses of the epithelium (E), connective tissue (CT), newly formed cementum (NC), new bone (NB), and total newly formed tissues (NFT). Results The test side showed smaller mean of NC (3.6 +/- 1.2), NB (2.1 +/- 0.7), and NFT (7.7 +/- 0.8) than the control group (NC 7.3 +/- 0.5; NB 5.3 +/- 1.3; NFT 10.1 +/- 2.2; P<0.05). No statistically significant differences were verified for E (test 3.1 +/- 2.0; control 2.8 +/- 2.1; P>0.05) and CT (test 2.5 +/- 1.1; control 2.0 +/- 0.5; P>0.05) between groups. Conclusion The bioabsorbable membrane was more effective in maintaining the space for periodontal regeneration than periosteal connective graft when used as barrier. Clinical relevance The bioabsorbable membrane showed more favorable regenerative results in intrabony defects in dogs than the subepithelial connective tissue graft as biological barrier. (AU)

• Processo FAPESP: 03/12810-5 - Utilizacao de enxerto de tecido conjuntivo subperiosteal no tratamento de lesoes periodontais infra-osseas. estudo clinico e radiografico em humanos; e clinico radiografico e histomorfometrico...
• Beneficiário: Fernando Salimon Ribeiro
• Modalidade de apoio: Bolsas no Brasil - Doutorado