| Texto completo | |
| Autor(es): |
Lourenco Neto, Natalino
[1]
;
Marques, Nadia C. T.
[1]
;
Fernandes, Ana Paula
[1]
;
Rodini, Camila O.
[2]
;
Sakai, Vivien T.
[3]
;
Abdo, Ruy Cesar C.
[1]
;
Machado, Maria Aparecida A. M.
[1]
;
Santos, Carlos F.
[2]
;
Oliveira, Thais M.
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, Bauru, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Bauru, SP - Brazil
[3] Univ Fed Alfenas, Dept Clin & Surg, Alfenas, MG - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS; v. 104, n. 1, p. 165-169, JAN 2016. |
| Citações Web of Science: | 8 |
| Resumo | |
The aim of this study was to evaluate the immunolocalization of dentin matrix protein (DMP)-1 in human primary teeth treated with different pulp capping materials. Twenty-five primary molars were divided into the following groups: formocresol (FC), calcium hydroxide (CH), mineral trioxide aggregate (MTA), corticosteroid/antibiotic solution+CH (O+CH), and Portland cement (PC), and all received conventional pulpotomy treatment. The teeth at the regular exfoliation period were extracted for histological analysis and immunolocalization of DMP-1. Statistical analysis was performed using the (2) test (p<0.05). Histological analysis revealed statistically significant differences in the comparison among the groups through the use of a score system regarding the presence of hard tissue barrier, odontoblastic layer, and internal resorption, but not regarding pulp calcification. Immunohistochemical analysis showed immunostaining for DMP-1 in groups CH, MTA, O+CH, and PC. Internal resorption was observed in the groups FC and CH. MTA and PC showed pulp repair without inflammation and with the presence of hard tissue barrier. DMP-1 immunostaining was higher for MTA and PC, confirming the reparative and bioinductive capacity of these materials. (c) 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 165-169, 2016. (AU) | |
| Processo FAPESP: | 09/11284-4 - Fator de crescimento endotelial vascular na reposta pulpar após o uso de material capeador precedido por anti-inflamatório ou laser de baixa intensidade em pulpotomias de dentes decíduos humanos |
| Beneficiário: | Thais Marchini de Oliveira Valarelli |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |