Nanobiotechnology of Carbon Dots: A Review

Autor(es)

Duran, Nelson ^{[1, 2, 3]} ; Simoes, Mateus B. ^[1] ; de Moraes, Ana C. M. ^{[1, 4]} ; Favaro, Wagner J. ^{[1, 5]} ; Seabra, Amedea B. ^{[6, 1]}

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Inst Chem, Lab Nanomat Synth & Biol Interact NanoBioss, BR-13083970 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, Inst Chem, Biol Chem Lab, CP 6154, BR-13083970 Campinas, SP - Brazil

^[3] Natl Nanotechnol Lab LNNano CNPEM, BR-13083970 Campinas, SP - Brazil

^[4] Univ Estadual Campinas, Inst Chem, Lab Solid State Chem, BR-13083970 Campinas, SP - Brazil

^[5] Univ Estadual Campinas, Inst Biol, Lab Urogenital Carcinogenesis & Immunotherapy LCU, BR-13083970 Campinas, SP - Brazil

^[6] Univ Fed Sao Paulo, Exact & Earth Sci Dept, BR-09913030 Diadema, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: JOURNAL OF BIOMEDICAL NANOTECHNOLOGY; v. 12, n. 7, p. 1323-1347, JUL 2016.
• Citações Web of Science: 16

Resumo

In recent years, carbon dots (CDs) have gained increasing attention owing to their unique properties and enormous potential for several biomedical and technological applications. CDs are biocompatible, have a small size with a relatively large surface area, are photostable, and have customizable photoluminescence properties. This review is divided into the following discussions of CDs: general definitions; an overview of recent reviews; methods of green and classical synthesis; applications in bioimaging, involving supercapacitors, nanocarriers and nanomedicine; toxicological evaluations (including cytotoxic, genotoxic and anti-cancer properties of CDs); their conjugation with enzymes, biosensors, and cell labeling. Finally the remaining drawbacks and challenges of CD applications are highlighted. In this context, this article aims to provide critical insight and inspire further developments in the synthesis and application of CDs. (AU)

• Processo FAPESP: 12/22612-5 - Estudo da Síntese de Carbon Dots via Carbonização Hidrotérmica e Avaliação Frente à Biossistemas
• Beneficiário: Mateus Batista Simões
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 12/17053-7 - Nanopartículas doadoras de óxido nítrico para aplicações biomédicas
• Beneficiário: Amedea Barozzi Seabra
• Modalidade de apoio: Auxílio à Pesquisa - Regular