| Texto completo | |
| Autor(es): |
Pinto, Ana Jessica
;
Benatti, Fabiana Braga
;
Roschel, Hamilton
;
de Sa Pinto, Ana Lucia
;
Silva, Clovis Artur
;
Elias Sallum, Adriana Maluf
;
Gualano, Bruno
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Revista Brasileira de Reumatologia; v. 56, n. 6, p. 509-514, NOV-DEC 2016. |
| Citações Web of Science: | 1 |
| Resumo | |
Objective: To compare muscle strength (i.e. lower- and upper-body strength) and function between physically inactive childhood-onset systemic lupus erythematosus patients (C-SLE) and healthy controls (CTRL). Methods: This was a cross-sectional study and the sample consisted of 19 C-SLE (age between 9 and 18 years) and 15 CTRL matched by age, sex, body mass index (BMI), and physical activity levels (assessed by accelerometry). Lower- and upper-body strength was assessed by the one-repetition-maximum (1-RM) test. Isometric strength was assessed through a handgrip dynamometer. Muscle function was evaluated by the timed-stands test (TST) and the timed-up-and-go test (TUG). Results: When compared with CTRL, C-SLE showed lower leg-press and bench-press 1-RM (p = 0.026 and p = 0.008, respectively), and a tendency toward lower handgrip strength (p = 0.052). C-SLE showed lower TST scores (p = 0.036) and a tendency toward higher TUG scores (p = 0.070) when compared with CTRL. Conclusion: Physically inactive C-SLE patients with very mild disease showed reduced muscle strength and functionality when compared with healthy controls matched by physical activity levels. These findings suggest C-SLE patients may greatly suffer from a physically inactive lifestyle than healthy controls do. Moreover, some sub-clinical ``residual{''} effect of the disease or its pharmacological treatment seems to affect C-SLE patients even with a well-controlled disease. (C) 2016 Elsevier Editora Ltda. (AU) | |
| Processo FAPESP: | 13/13126-2 - Avaliação do nível de atividade física em pacientes com dermatomiosite juvenil e lúpus eritematoso sistêmico juvenil. |
| Beneficiário: | Ana Jéssica Pinto |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |