Effects of negatively and positively charged Ti metal surfaces on ceramic coating adhesion and cell response

Autor(es)

do Nascimento, Rodney Marcelo ; de Carvalho, Vanessa Rafaela ; Govone, Jose Silvio ; Hernandes, Antonio Carlos ; da Cruz, Nilson Cristino

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE; v. 28, n. 2 FEB 2017.
• Citações Web of Science: 5
• Assunto(s): Ósseointegração Teste de biocompatibilidade

Resumo

This manuscript reports an evaluation of the effects of simple chemical-heat treatments on the deposition of different ceramic coatings, i.e., TiO2, CaTiO3 and CaP, on commercially pure titanium (cp-Ti) and Ti6Al4V and the influence of the coatings on cells interaction with the surfaces. The ceramic materials were prepared by the sol-gel method and the coating adhesion was analyzed by pull-off bending tests. The wettability of positively or negatively charged surfaces was characterized by contact angle measurements, which also enabled the calculation of the surface free energy through the polar-apolar liquids approach. Both acid and alkaline treatments activated the cp-Ti, whereas Ti6Al4V was only activated by the alkaline treatment. Such treatment led to increased hydrophilicity with inhibition of the fibroblastic response on Ti6Al4V. On the other hand, osteoblastic cells adhered to and proliferated on the positively and negatively charged surfaces. The maximum adhesion strength (similar to 3400N) was obtained with a negative Ti6Al4V-CaTiO3-CaP multilayer surface. (AU)

• Processo FAPESP: 13/21970-8 - Desenvolvimento de biomaterial a partir da incorporação de fosfatos de cálcio em estruturas de látex visando aplicação como dispositivo de liberação controlada
• Beneficiário: Rodney Marcelo do Nascimento
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado