Simple, Expendable, 3D-Printed Microfluidic Systems for Sample Preparation of Petroleum

Autor(es)

Kataoka, Erica M. ; Murer, Rui C. ; Santos, Jandyson M. ; Carvalho, Rogerio M. ; Eberlin, Marcos N. ; Augusto, Fabio ; Poppi, Ronei J. ; Gobbi, Angelo L. ; Hantao, Leandro W.

• Tipo de documento: Artigo Científico
• Fonte: Analytical Chemistry; v. 89, n. 6, p. 3460-3467, MAR 21 2017.
• Citações Web of Science: 27

Resumo

In this study, we introduce a simple protocol to manufacture disposable, 3D-printed microfluidic systems for sample preparation of petroleum. This platform is produced. with a consumer-grade 3D-printer, using fused deposition modeling. Successful incorporation of solid-phase extraction (SPE) to microchip was ensured by facile 3D element integration using proposed approach. This 3D-printed piSPE device was applied to challenging matrices in oil and gas industry, such as crude oil and oil brine emulsions. Case studies investigated important limitations of nonsilicon and nonglass microchips, namely, resistance to nonpolar solvents and conservation of sample integrity. Microfluidic features remained fully functional even after prolonged exposure to nonpolar solvents (20 min). Also, 3D-printed liSPE devices enabled fast emulsion breaking and solvent deasphalting of petroleum, yielding high recovery values (98%) without compromising maltene integrity. Such finding was ascertained by high-resolution molecular analyses using comprehensive two-dimensional gas chromatography and gas chromatography/mass spectrometry by monitoring important biomarker classes, such as C10 demethylated terpanes, aaa-steranes, and monoaromatic steroids. 3D-Printed chips enabled faster and reliable preparation of maltenes by exhibiting a 10-fold reduction in sample processing time, compared to the reference method. Furthermore, polar (oxygen-, nitrogen-,-and sulfur-containing) analytes found in low-concentrations were analyzed by Fourier transform ion cyclotron resonance mass spectrometry. Analysis results demonstrated that accurate characterization may be accomplished for most classes of polar compounds, except for asphaltenes, which exhibited lower recoveries (82%) due to irreversible adsorption to sorbent phase. Therefore, 3D-printing is a compelling alternative to existing microfabrication solutions, as robust devices were easy to prepare and operate. (AU)

• Processo FAPESP: 13/19161-4 - Petroleômica por FT-MS: Novas Estratégias de Caracterização por Pré-fracionamento de Óleos Contaminados e Emulsificados
• Beneficiário: Jandyson Machado Santos
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 15/05059-9 - Desenvolvimento e avaliação de moduladores microfluídicos planares e livre de consumíveis para cromatografia gasosa bidimensional abrangente
• Beneficiário: Leandro Wang Hantao
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 14/00228-4 - Miologia do ombro, braço e antebraço da paca (L.1766)
• Beneficiário: Juliana Aparecida Do Carmo Emidio e Silva
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica