The interaction between erectile dysfunction complaints and depression in men: a cross-sectional study about sleep, hormones and cl uality of life

Autor(es)

Soterio-Pires, J. H. ; Hirotsu, C. ; Kim, L. J. ; Bittencourt, L. ; Tufik, S. ; Andersen, M. L.

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH; v. 29, n. 2, p. 70-75, MAR-APR 2017.
• Citações Web of Science: 9

Resumo

Depression (DEP) is one of the main disabling diseases and is considered a contributor factor for erectile dysfunction (ED). Both of these conditions may be associated with hormonal changes and sleep disturbances. We aimed to evaluate the interaction between ED complaints and depression symptoms on sleep parameters, hormone levels and quality of life in men. This was a cross-sectional study of 468 men aged 20-80 years. The participants were classified according to the presence of ED and/or DEP in groups of healthy individuals, ED, DEP and DEP with ED (DEP-ED). All participants completed questionnaires about sleep, clinical history and quality of life, and underwent polysomnography with blood collection the{''} following morning. ED participants showed higher frequency of insomnia symptornt (65.5%), whereas DEP group had more complaints of difficulty in falling asleep.anci early morning awakening. In the polysomnography, all groups showed similar parameters. No differences were found in cortisol and total testosterone levels; however, free testosterone levels and the physiological domain of quality of life were lower in DEP-ED group. ED and DEP, as independent factors, negatively affected subjective sleepparameters. The interaction between these factors led to a low quality of life and was related to a decrease in free testosterone levels. (AU)

• Processo FAPESP: 15/02036-8 - Efeitos do aumento da transmissão dopaminérgica durante o período de adolescência sobre o comportamento sexual de ratos adultos
• Beneficiário: Jhon Helbert Soterio Pires
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 15/19136-5 - Efeitos da sonolência excessiva diurna ou da insônia associadas à apneia obstrutiva do sono no risco cardiovascular: um estudo longitudinal prospectivo de base populacional
• Beneficiário: Lenise Jihe Kim
• Modalidade de apoio: Bolsas no Brasil - Doutorado