Autor(es)

Dolan, Eimear ^[1] ; Swinton, Paul A. ^[2] ; Sale, Craig ^[3] ; Healy, Aoife ^[4] ; O'Reilly, John ^[5]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sao Paulo - Brazil

^[2] Robert Gordon Univ, Sch Hlth Sci, Aberdeen - Scotland

^[3] Nottingham Trent Univ, Sch Sci & Technol, Musculoskeletal Physiol Res Grp, Sports Hlth & Performance Enhancement Res Ctr, Nottingham - England

^[4] Staffordshire Univ, Sch Life Sci & Educ, CSHER, Stoke On Trent, Staffs - England

^[5] Chinese Univ Hong Kong, Dept Sport Sci & Phys Educ, Sha Tin, Hong Kong - Peoples R China

• Tipo de documento: Artigo de Revisão
• Fonte: NUTRITION REVIEWS; v. 75, n. 10, p. 858-870, OCT 2017.
• Citações Web of Science: 16

Resumo

Context: The scientific literature shows conflicting evidence about the relationship between adiposity and bone mass in overweight and obese populations. Objective: The aim of this review was to quantify the correlation between adipose mass (absolute and relative) and bone mineral density (BMD) in overweight and obese populations. Data Sources: Three databases were searched electronically. In addition, reference lists of relevant articles were screened. Study Selection: A total of 16 studies, comprising 2587 participants and 75 correlation coefficients were selected for inclusion in the review. Data Extraction: Data were extracted from each study using a standardized form. Results: Multilevel modeling indicated opposing relationships between BMD and adiposity: absolute adiposity correlated positively, and relative adiposity negatively, with BMD. Sex and age were the primary moderators of these relationships. Strong evidence supported a negative relationship between relative adipose mass and BMD in men (R = -0.37; 95% CI, -0.57 to -0.12) and in those aged less than 25 years (R = -0.28; 95% CI, -0.45 to -0.08). Conclusion: To prevent bone loss in overweight and obese populations, nutrition-and exercise-based interventions that focus on a controlled reduction of adipose mass with concomitant preservation of lean mass are recommended. (AU)

• Processo FAPESP: 15/11328-2 - Metabolismo da carnosina no músculo esquelético: um estudo de múltiplas abordagens. Sub-estudo 3: explorando o papel da carnosina no músculo esquelético
• Beneficiário: Eimear Bernadette Dolan
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado