Vaccinia virus in Feces and Urine of Wild Rodents from SAo Paulo State, Brazil

Autor(es):Mostrar menos -

Peres, Marina G. ^[1] ; Bacchiega, Thais S. ^[1] ; Appolinario, Camila M. ^[1] ; Vicente, Acacia F. ^[1] ; Mioni, Mateus S. R. ^[1] ; Ribeiro, Bruna L. D. ^[1] ; Fonseca, Clovis R. S. ^[1] ; Pelicia, Vanessa C. ^[1] ; Ferreira, Fernando ^[2] ; Abrahao, Jonatas S. ^[3] ; Megid, Jane ^[1]

Afiliação do(s) autor(es)

^[1] UNESP Univ Estadual Paulista, Fac Med Vet & Zootecnia, BR-18618970 Botucatu, SP - Brazil

^[2] Univ Sao Paulo, Fac Med Vet & Zootecnia, BR-05508270 Sao Paulo - Brazil

^[3] UFMG Univ Fed Minas Gerais, Inst Ciencias Biol, BR-31270901 Belo Horizonte, MG - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Viruses-Basel; v. 10, n. 2 FEB 2018.
• Citações Web of Science: 0

Resumo

The origin of Vaccinia virus (VACV) outbreaks in Brazil remains unknown, but since the isolation of VACV in Mus musculus mice during a zoonotic outbreak affecting cattle and milkers, peridomestic rodents have been suggested to be a link between cows and wild animals. Considering that experimentally infected mice eliminate viral particles in their feces, we investigated the presence of VACV in the feces and urine of wild rodents that were captured in the forest areas surrounding milking farms in the central west region of SAo Paulo State. For the first time, this work reports the detection of VACV by PCR in the feces of naturally infected Oligoryzomys flavescens, Oligoryzomys nigripes, and Sooretamys angouya, and in the urine of Oligorizomys flavescens, which raises important questions about the spread of VACV by rodent feces and its potential to induce clinical infections in cows. (AU)

• Processo FAPESP: 13/07693-1 - Análise filogenética do vírus Vaccínia (VACV) circulante em animais silvestres e domésticos da região Centro Oeste do estado de São Paulo
• Beneficiário: Marina Gea Peres Serafim
• Modalidade de apoio: Bolsas no Brasil - Doutorado