Effects of Photobiomodulation on SOFAT, A T-cell-derived Cytokine, May Explain Accelerated Orthodontic Tooth Movement

Autor(es)

Jettar, Viviane ^[1] ; Napimoga, Marcelo H. ^[2] ; Freitas, Fabiana ^[3] ; Clemente-Napimoga, Juliana T. ^[4] ; Suzuki, Selly S. ^[1] ; Montalli, Victor A. ^[2] ; Garcez, Aguinaldo S. ^[1]

Afiliação do(s) autor(es)

^[1] Sao Leopoldo Mandic Inst & Res Ctr, Orthodont, Campinas, SP - Brazil

^[2] Sao Leopoldo Mandic Inst & Res Ctr, Campinas, SP - Brazil

^[3] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Physiol, Piracicaba, SP - Brazil

^[4] Sao Leopoldo Mandic Inst & Res Ctr, Physiol, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Photochemistry and Photobiology; v. 94, n. 3, p. 604-610, MAY-JUN 2018.
• Citações Web of Science: 2

Resumo

Orthodontic tooth movement is based on mechanical forces inducing bone remodeling, and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFATa secreted osteoclastogenic factor of activated T cells and RANK-L during tooth movement. The results showed that tooth displacement, RANK-L and SOFAT levels were significantly greater compared to Control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity. (AU)

• Processo FAPESP: 13/06079-8 - Avaliação histológica e imunohistoquímica da ação da terapia laser de baixa potência na prevenção da reabsorção radicular durante movimentação ortodôntica
• Beneficiário: Aguinaldo Silva Garcez Segundo
• Modalidade de apoio: Auxílio à Pesquisa - Regular