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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effects of Photobiomodulation on SOFAT, A T-cell-derived Cytokine, May Explain Accelerated Orthodontic Tooth Movement

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Jettar, Viviane [1] ; Napimoga, Marcelo H. [2] ; Freitas, Fabiana [3] ; Clemente-Napimoga, Juliana T. [4] ; Suzuki, Selly S. [1] ; Montalli, Victor A. [2] ; Garcez, Aguinaldo S. [1]
Total Authors: 7
[1] Sao Leopoldo Mandic Inst & Res Ctr, Orthodont, Campinas, SP - Brazil
[2] Sao Leopoldo Mandic Inst & Res Ctr, Campinas, SP - Brazil
[3] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Physiol, Piracicaba, SP - Brazil
[4] Sao Leopoldo Mandic Inst & Res Ctr, Physiol, Campinas, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Photochemistry and Photobiology; v. 94, n. 3, p. 604-610, MAY-JUN 2018.
Web of Science Citations: 2

Orthodontic tooth movement is based on mechanical forces inducing bone remodeling, and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFATa secreted osteoclastogenic factor of activated T cells and RANK-L during tooth movement. The results showed that tooth displacement, RANK-L and SOFAT levels were significantly greater compared to Control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity. (AU)

FAPESP's process: 13/06079-8 - Histological and immunohistochemical evaluation of low-level laser therapy to prevent root resorption during orthodontic tooth movement
Grantee:Aguinaldo Silva Garcez Segundo
Support type: Regular Research Grants