Protective effects of photobiomodulation against resistance exercise-induced muscle damage and inflammation in rats

Autor(es):Mostrar menos -

de Oliveira, Helenita Antonia ^[1] ; Antonio, Ednei Luiz ^[2] ; Silva, Flavio Andre ^[2] ; Camillo de Carvalho, Paulo de Tarso ^[1] ; Feliciano, Regiane ^[1] ; Yoshizaki, Amanda ^[2] ; Vieira, Stella de Souza ^[2] ; de Melo, Brunno Lemes ^[2] ; Pinto Leal-Junior, Ernesto Cesar ^[1] ; Labat, Rodrigo ^[3] ; Bocalini, Danilo Sales ^{[4, 5]} ; Silva Junior, Jose Antonio ^[1] ; Ferreira Tucci, Paulo Jose ^[2] ; Serra, Andrey Jorge ^[1]

Afiliação do(s) autor(es)

^[1] Nove Julho Univ, Lab Biophoton, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Sao Paulo - Brazil

^[3] Nove Julho Univ, Postgrad Program Biophoton Appl Hlth Sci, Sao Paulo - Brazil

^[4] Univ Sao Judas Tadeu, Translat Physiol Lab, Sao Paulo - Brazil

^[5] Univ Sao Judas Tadeu, Phys Educ & Aging Sci Program, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF SPORTS SCIENCES; v. 36, n. 20, p. 2349-2357, 2018.
• Citações Web of Science: 4

Resumo

We investigated whether low-level laser therapy (LLLT) prior to or post resistance exercise could attenuate muscle damage and inflammation. Female Wistar rats were assigned to non-LLLT or LLLT groups. An 830-nm DMC Laser Photon III was used to irradiate their hind legs with 2J, 4J, and 8J doses. Irradiations were performed prior to or post (4J) resistance exercise bouts. Resistance exercise consisted of four maximum load climbs. The load work during a resistance exercise bout was similar between Control (non-LLLT, 225 +/- 10g), 2J (215 +/- 8g), 4J (210 +/- 9g), and 8J (226 +/- 9g) groups. Prior LLLT did not induce climbing performance improvement, but exposure to 4J irradiation resulted in lower blood lactate levels post-exercise. The 4J dose decreased creatine kinase and lactic dehydrogenase levels post-exercise regardless of the time of application. Moreover, 4-J irradiation exposure significantly attenuated tumor necrosis factor alpha, interleukin-6, interleukin-1, cytokine-induced neutrophil chemoattractant-1, and monocyte chemoattractant protein-1. There was minor macrophage muscle infiltration in 4J-exposed rats. These data indicate that LLLT prior to or post resistance exercise can reduce muscle damage and inflammation, resulting in muscle recovery improvement. We attempted to determine an ideal LLLT dose for suitable results, wherein 4J irradiation exposure showed a significant protective role. (AU)

• Processo FAPESP: 15/11028-9 - A modalidade de treinamento físico aeróbio pode determinar a existência de remodelamento cardíaco: identificando peculiaridades estruturais, funcionais e moleculares dos modelos experimentais de natação e corrida
• Beneficiário: Andrey Jorge Serra
• Modalidade de apoio: Auxílio à Pesquisa - Regular