Visible-Light-Driven Epoxyacylation and Hydroacylation of Olefins Using Methylene Blue/Persulfate System in Water

Autor(es)

de Souza, Gabriela F. P. ^[1] ; Bonacin, Juliano A. ^[2] ; Salles, Jr., Airton G. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Inst Chem, Dept Organ Chem, POB 6154, BR-13084862 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, Inst Chem, Dept Inorgan Chem, POB 6154, BR-13084862 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Organic Chemistry; v. 83, n. 15, p. 8331-8340, AUG 3 2018.
• Citações Web of Science: 7

Resumo

A visible-light-driven strategy for hydroacylation and epoxyacylation of olefins in water using methylene blue as photoredox catalyst and persulfate as oxidant is reported. In this unprecedented unified approach, two different transformations are accomplished using only one set of reagents. The method has a broad scope spanning a range of aromatic and aliphatic aldehydes as well as conjugated and nonconjugated olefins to deliver ketones and epoxyketones from abundant and inexpensive chemical feedstocks. (AU)

• Processo FAPESP: 17/18400-6 - Oxidação alílica/benzílica seguida de adição de Michael/reação aldólica em um único frasco: Uso do TBAI como catalisador comum para ambas as etapas visando aumento da complexidade estrutural.
• Beneficiário: Airton Goncalves Salles Junior
• Modalidade de apoio: Auxílio à Pesquisa - Regular