Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

Autor(es)

Luís Fábio da Silva Batista ; Vânia Lúcia Ribeiro da Matta ^[2] ; Thaise Yumie Tomokane ^[3] ; Acácio Duarte Pacheco ^[4] ; Fernando Tobias Silveira ; Claudio Nazaretian Rossi ^[6] ; Mary Marcondes ^[7] ; Márcia Dalastra Laurenti ^[8]

• Tipo de documento: Artigo Científico
• Fonte: Revista da Sociedade Brasileira de Medicina Tropical; v. 49, n. 3, p. 361-364, 2016-06-00.

Resumo

Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas. (AU)

• Processo FAPESP: 12/50285-9 - Avaliação clinica,imunologica e suas correlações com marcadores genéticos na leishmaniose visceral canina
• Beneficiário: Marcia Dalastra Laurenti
• Modalidade de apoio: Auxílio à Pesquisa - Regular